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Displaying results 1281 - 1290 of 10000 in total
  1. Drug

    Phenyl salicylate

    go.drugbank.com/drugs/DB11071
    Approved

    Phenyl salicylate is a 2-hydroxybenzoic acid phenyl ester. It is utilized in some manufacturing processes of polymers, lacquers, adhesives, waxes, as well as polishes. … It is synthesized by heating salicylic acid with phenol [L2468], [MSDS]. Phenyl salicylate is used as a food additive in the USA [L2479].

    Mixtures: Urin D/S, Uretron D/S
  2. Drug

    Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10793
    ApprovedInvestigational

    A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.

    Synonyms: Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated)Mixtures: INFLUVAC S TETRA, INFLUVAC S TETRA
  3. Drug

    Fluconazole

    go.drugbank.com/drugs/DB00196
    ApprovedInvestigational

    Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. … This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole].

    Mixtures: FUNEX® - S TABLETA, BATEN ® S TABLETAS RECUBIERTASCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors
  4. Drug

    Ivacaftor

    go.drugbank.com/drugs/DB08820
    ApprovedInvestigational

    Ivacaftor (also known as Kalydeco or VX-770) is a drug used for the management of Cystic Fibrosis (CF). It is manufactured and distributed by Vertex Pharmaceuticals. … [L6841] Ivacaftor is administered as a monotherapy and also administered in combination with other drugs for the management of CF.

    Synonyms: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamideCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  5. Drug

    Dactylis glomerata pollen

    go.drugbank.com/drugs/DB10379
    Approved

    Dactylis glomerata pollen is the pollen of the Dactylis glomerata plant. Dactylis glomerata pollen is mainly used in allergenic testing.

    Mixtures: GRASS MIX Number 4-S, GRASS MIX Number 4-S
  6. Drug

    Repinotan

    go.drugbank.com/drugs/DB06506
    Investigational

    Repinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective properties.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  7. Drug

    Edaxeterkib

    go.drugbank.com/drugs/DB21490
    Investigational

    Edaxeterkib is a small molecule drug. The usage of the INN stem '-terkib' in the name indicates that Edaxeterkib is a extracellular signal-regulated kinase (ERK) inhibitor. … Edaxeterkib is under investigation in clinical trial NCT03051035 (First-in-Human Study of KO-947 in Non-Hematological Malignancies). Edaxeterkib has a monoisotopic molecular weight of 469.22 Da.

  8. Drug

    Measles virus vaccine live attenuated

    go.drugbank.com/drugs/DB10315
    ApprovedInvestigational

    Measles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles, which is a common childhood disease. … The vaccine is prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture.

    Mixtures: PROQUAD® ( Measles, Mumps, Rubella AND Varicella (Oka/Merck) Virus Vaccine Live, MSD) LYOPHILIZED VACCINE;, TRESIVAC 0,5 ML SC ENJEKSIYONLUK ÇÖZELTI IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 1 ADETSynonyms: Measles virus live antigen, A
  9. Pathway

    Gs Serotonergic Smooth Muscle Contraction

    smpdb.ca/view/SMP0127045
    Physiological

    Serotonergic (5-HT4) receptors are typically coupled to Gs proteins. Activation of Gs proteins stimulates adenylate cyclase (AC), leading to increased production of cyclic AMP (cAMP) from ATP.Gs proteins stimulate adenylate cyclase (AC) ...

    Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
  10. Target

    Maternal embryonic leucine zipper kinase

    go.drugbank.com/bio_entities/BE0009486
    TargetHumans

    Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 an...

    Synonyms: Tyrosine-protein kinase MELK