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Metoprolol Action Pathway
smpdb.ca/view/SMP0000302Drug actionMetoprolol (also known as Lopressor) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Metoprolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the binding of o...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Pindolol Action Pathway
smpdb.ca/view/SMP0000306Drug actionPindolol (also known as Visken) a beta blocker (non-selective) that block beta-1 adrenergic receptor in heart. Blocking beta-1 adrenergic receptor could prevent the binding of epinephrine and norepinephrine, which could efficiently reduc...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Labetalol Action Pathway
smpdb.ca/view/SMP0000368Drug actionLabetalol (also known as Albetol or Ibidomide) is an inhibitor/antagonist of beta-1 adrenergic receptor that can be used for treating high blood pressure and reducing cardiac output. Labetalol can bind to beta-1 adrenergic receptor on bo...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Felodipine Action Pathway
smpdb.ca/view/SMP0000377Drug actionFelodipine is a medication used to treat hypertension (high blood pressure). Untreated hypertension can lead to a heart attack, heart disease or stroke. High sodium intake can contribute to hypertension. Felodipine works by blocking calc...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Isradipine Action Pathway
smpdb.ca/view/SMP0000378Drug actionIsradipine (also known as DynaCirc or Prescal) is a calcium channel blocker within dihydropyridine (DHP) class that can be used for treating high blood pressure and essential hypertension. There are at least 5 different types of calcium ...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Bopindolol Action Pathway
smpdb.ca/view/SMP0000657Drug actionBopindolol (also known as Sandonorm) is a selective β1 adrenergic receptor antagonist (beta blocker), which can be used for treatment of high blood pressure (hypertension) and irregular heartbeats (arrhythmias). Bopindolol also has ...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Epinephrine Action Pathway
smpdb.ca/view/SMP0000661Drug actionEpinephrine can be derived from phenylalanine and tyrosine and it is an active sympathomimetic hormone that can be secreted from adrenal medulla. Epinephrine can stimulate alpha- and beta- adrenergic systems by binding on alpha-1 and bet...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Isoprenaline Action Pathway
smpdb.ca/view/SMP0000663Drug actionIsoprenaline (also known as isoproterenol) is a selective beta adrenergic bronchodilator that can be used for treating slow heart rate (bradycardia), heart block, and rarely for asthma. Isoprenaline can bind and inhibit beta-1 adrenergic...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Arbutamine Action Pathway
smpdb.ca/view/SMP0000664Drug actionArbutamine is a synthetic catecholamine used to initiate a cardiac stress response to mimic exercise to detect coronary artery disease. Arbutamine has nonselective beta and weak alpha-1-adrenergic activity which causes increased chronotr...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4Bevantolol Action Pathway
smpdb.ca/view/SMP0000668Drug actionBevantolol hydrocholride, also known as bevantolol, is a cardioselective beta blocker prescribed to treat angina pectoris and hypertension. Bevantolol is an antagonist of beta-1 adrenoreceptors to block the G protein signalling cascade a...
Enzymes: Potassium channel subfamily K member 1, Inward rectifier potassium channel 4