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Eribulin
go.drugbank.com/drugs/DB08871ApprovedInvestigationalEribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic
Products: HALAVEN 0.5 mg/ml solution for injection, Eribulin Advanz Pharma 0,44 mg/ml InjektionslösungTranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalA propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and p...
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 CYP1A2 InhibitorsProducts: Tranylcypromin Aristo 10 mg Filmtabletten, Tranylcypromin Aristo 20 mg FilmtablettenBosentan
go.drugbank.com/drugs/DB00559ApprovedInvestigationalBosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure. … Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InducersSynonyms: p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide, 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamideVerteporfin
go.drugbank.com/drugs/DB00460ApprovedInvestigationalVerteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: [CL-315555] and [CL-315585]. … oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels.
Products: VISUDYNE 15 MG INFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, VISUDYNE FOR INJECTION 15 mg/vialElranatamab
go.drugbank.com/drugs/DB15395ApprovedInvestigationallight chain to drug structure. … [L47820] Elranatamab was also approved by the European Commission on December 8, 2023.[L50437]
Categories: Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engagerSynonyms: IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL SURFACE ANTIGEN T3/LEU-4 EPSILON CHAIN)), HUMAN-MUS MUSCULUS MONOCLONAL DISULFIDE WITH IMMUNOGLOBULINAxitinib
go.drugbank.com/drugs/DB06626ApprovedInvestigationalIt is reported to exhibit potency that is 50-450 times higher than that of the first generation VEGFR inhibitors.[L6676] Axitinib is an indazole derivative. … Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: INLYTA (TABLETS 5 MG), Axitinib STADA 5 mg FilmtablettenNonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnIn several European countries, spermicides are no longer on the market. … N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants.
Products: OKSİNOL 150 MG OVÜLGonadorelin
go.drugbank.com/drugs/DB00644ApprovedInvestigationalVet approvedGonadorelin is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis. GnRH is responsible for the release of follicle stimulating hormone and leutinizing hormon...
Mixtures: Relisorm 100 for Inj.-pws Liq-kit Sc IV, Relisorm 500 for Inj.-pws Liq-kit IV ScProducts: Kryptocur 0,2 mg/0,1 ml - nasale Sprühlösung, LH-RH FERRING 0,1 MG/ML IV ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADETTrabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalIt binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair machinery. … It is currently under evaluation for the treatment of breast cancer, prostate cancer, in addition to pediatric sarcomas. Both the European Commission and the U.S.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesProducts: YONDELIS 1 MG IV KONSANTRE INFUZYONLUK COZELTI ICIN TOZ, Yolisar 1 mg I.V. İnfüzyonluk Çözelti Hazırlamada Kullanılacak Konsantre İçin Toz, 1 ADETZotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawn[L1082] When the analysis of antipsychotics was retaken in 2016 by the FDA, zotepine did not reach the threshold effect to be further studied.[L1313]. … It was designed and synthesized by Fujisawa Pharmaceutical Co Ltd.[A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin 5-HT2 Receptor AntagonistsProducts: ZOLEPTIL © 50 MG TABLETAS RECUBIERTAS.