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Displaying results 1291 - 1300 of 2256 in total
  1. Target

    Nuclear receptor subfamily 4 group A member 3

    go.drugbank.com/bio_entities/BE0008998
    TargetHumans

    In mast cells activated by Fc-epsilon receptor cross-linking, promotes the synthesis and release of cytokines but impairs events leading to degranulation (By similarity).

    Polypeptides: Nuclear receptor subfamily 4 group A member 3Synonyms: Nuclear hormone receptor NOR-1, Neuron-derived orphan receptor 1
  2. Target

    Nuclear receptor subfamily 1 group D member 2

    go.drugbank.com/bio_entities/BE0009348
    TargetHumans

    Acts as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. … Regulates lipid and energy homeostasis in the skeletal muscle via repression of genes involved in lipid metabolism and myogenesis including: CD36, FABP3, FABP4, UCP3, SCD1 and MSTN.

    Polypeptides: Nuclear receptor subfamily 1 group D member 2Synonyms: Rev-erb alpha-related receptor, Orphan nuclear hormone receptor BD73
  3. Target

    Leukocyte immunoglobulin-like receptor subfamily A member 4

    go.drugbank.com/bio_entities/BE0013620
    TargetHumans

    Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354).

    Polypeptides: Leukocyte immunoglobulin-like receptor subfamily A member 4
  4. Target

    Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

    go.drugbank.com/bio_entities/BE0020703
    TargetHumans

    Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter (PubMed:10713165, PubMed:20005308, PubMed:21376232).

    Polypeptides: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
  5. Drug

    Racemethionine

    go.drugbank.com/drugs/DB13972
    Approved

    A preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.

    Mixtures: Vita-vim - Tab, Vita Balance 2000
  6. Drug

    Malacidin B

    go.drugbank.com/drugs/DB14052
    Experimental

    Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin B appears to act via its own distinct mechanism.

  7. Drug

    Malacidin A

    go.drugbank.com/drugs/DB14051
    Experimental

    Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin A appears to act via its own distinct mechanism.

  8. Drug

    Aloe vera leaf

    go.drugbank.com/drugs/DB13906
    ApprovedInvestigational

    Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands.

  9. Drug

    Levetiracetam

    go.drugbank.com/drugs/DB01202
    ApprovedInvestigational

    possesses a wide therapeutic index[L8615,A185918] and little-to-no potential to produce, or be subject to, pharmacokinetic interactions[L8606,L8600,L8615] - these characteristics make it a desirable choice over

  10. Drug

    Drometrizole trisiloxane

    go.drugbank.com/drugs/DB11585
    Approved

    relatively few reports of adverse reactions, the FDA continues to cite that the existing scientific record is not sufficient to establish the compound as being generally recognized as safe and effective for over-the-counter