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Flax seed
go.drugbank.com/drugs/DB10708ApprovedFlax seed allergenic extract is used in allergenic testing.
Mixtures: Nature"s Gift CoQ10 PlusCyclic GMP
go.drugbank.com/drugs/DB02315ExperimentalIts levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed) … It is a cellular regulatory agent and has been described as a second messenger.
Synonyms: 3',5'-cyclic GMP, Guanosine 3',5'-cyclic phosphateCategories: Heterocyclic Compounds, 2-RingMuraglitazar
go.drugbank.com/drugs/DB06510InvestigationalMuraglitazar (Bristol-Myers Squibb/Merck) is a new agent under investigation for the treatment of patients with type 2 diabetes. … in LDL-C levels.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingGi Serotonergic Smooth Muscle Relaxation
smpdb.ca/view/SMP0126986PhysiologicalAlthough numerous GPCRs have the ability to couple to more than one heterotrimeric G protein, a given GPCR is typically classified based on the G protein subfamily (e.g., Gs, Gi/o, or Gq/11) it preferentially activates. Activation of the...
Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acidEnzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Metoclopramide Serotonergic Smooth Muscle Contraction
smpdb.ca/view/SMP0127039Drug actionMetoclopramide is a dopamine receptor antagonist and has been approved by the FDA to treat nausea and vomiting in patients with gastroesophageal reflux disease or diabetic gastroparesis by increasing gastric motility.. Metoclopramide wor...
Drugs: ATP · Metoclopramide · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate +1 moreEnzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortPrucalopride Action Pathway
smpdb.ca/view/SMP0127044Drug actionPrucalopride acts as a selective stimulator of the 5-HT4 receptors while having no interaction with hERG channel or 5-HT1 receptors which reduces significantly the cardiovascular risk found in other similar drugs. 5-HT4 receptors can be ...
Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid +1 moreEnzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortForetinib
go.drugbank.com/drugs/DB12307InvestigationalIt inhibits the activation of MET, RON, ERK and AKT, decreased proliferation and increased apoptosis. … Foretinib is an orally available small molecule compound designed to target multiple RTKs implicated in the development, progression and spread of cancer.
Categories: Heterocyclic Compounds, 2-RingRutin
go.drugbank.com/drugs/DB01698ApprovedInvestigationalA flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Mixtures: KORDEL`S C TIME ACID FREE C 1000MG TABLET, KORDEL`S NUTRITIME TABLETCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersTrimebutine
go.drugbank.com/drugs/DB09089ApprovedInvestigationalTrimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries. … It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form.
Synonyms: 2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoatInternational brands: Newbutin SRSodium acetate
go.drugbank.com/drugs/DB09395ApprovedInvestigationalSodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. … Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct sodium levels in hyponatremic patients.
Synonyms: Acetic acid, sodium salt (1:1)Mixtures: B S S STERILE IRRIGATING SOLUTION, Isolyte S