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Cinacalcet
go.drugbank.com/drugs/DB01012ApprovedInvestigationalCinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. … It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Synonyms: (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine, N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amineProducts: CINACALCET DR. REDDY'SPancreatic Metastatic Cancer
go.drugbank.com/conditions/DBCOND0070216Synonyms: Secondary malignant deposit in pancreasEverolimus
go.drugbank.com/drugs/DB01590ApprovedInvestigationalIn a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and not on the mTORC2 protein. … Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: EVEROLIMUS DR. REDDY'SAluminum hydroxide
go.drugbank.com/drugs/DB06723ApprovedInvestigationalAluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. … Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Mixtures: Maalox oral suspension in sachet, MULTIGEL IIBosentan
go.drugbank.com/drugs/DB00559ApprovedInvestigationalBosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. … Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Synonyms: 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide, p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamideProducts: N/A, TRACLEER ® 62.5 MG TABLETAS RECUBIERTAS DE PELICULA.Severe Glabellar Frown Lines (GL)
go.drugbank.com/conditions/DBCOND0146865Synonyms: Severe Glabellar Frown Lines (GL)DNA damage-inducible transcript 4 protein
go.drugbank.com/bio_entities/BE0003445TargetHumansIts role in the response to hypoxia depends on the cell type; it mediates mTORC1 inhibition in fibroblasts and thymocytes, but not in hepatocytes (By similarity). … Plays a role in neuronal cell death
Synonyms: Protein regulated in development and DNA damage response 1Glutamic acid
go.drugbank.com/drugs/DB00142ApprovedInvestigationalNutraceuticalA peptide that is a homopolymer of glutamic acid.
Synonyms: L-Glutamate, L-Glutamic acidMixtures: Aminosyn II in Dextrose, Aminosyn II in DextroseXylometazoline
go.drugbank.com/drugs/DB06694ApprovedIn some countries, it is available as combination products with [ipratropium], [domiphen], or [dexpanthenol]. … [A228508] Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies.
Mixtures: Ophtrivin A Ophthalmic DpsProducts: Otrivin With M-D Pump, XYLOMETAZOLIN 0.1% APO DISLevodopa
go.drugbank.com/drugs/DB01235ApprovedInvestigationalLevodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label]. … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after
Synonyms: L-DOPA, 3-Hydroxy-L-tyrosineMixtures: LEVO/CA/EN 100/25/200 STD, LEVO/CA/EN 150/37.5/200STD