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Displaying results 1321 - 1330 of 4588 in total
  1. Pathway

    Edrophonium Action Pathway (new)

    smpdb.ca/view/SMP0126690
    Drug action

    Edrophonium is a cholinesterase inhibitor used in the treatment of myasthenia gravis, that works to prolong the duration of action of acetylcholine. The drug acts rapidly by binding to acetylcholinesterase and cholinesterase halting the ...

    Drugs: Choline · Edrophonium · Calcium · Magnesium cation · Acetylcholine · Acetic acid
    Enzymes: High affinity choline transporter 1
  2. Pathway

    Distigmine Action Pathway

    smpdb.ca/view/SMP0126700
    Drug action

    Distigmine is a cholinesterase inhibitor, a parasympathomimetic agent used in the treatment of neurogenic bladder dysfunction and or myasthenia gravis. This is an experimental drug that acts by inhibiting cholinesterase and also binds di...

    Drugs: Choline · Calcium · Magnesium cation · Acetylcholine · Acetic acid · Distigmine
    Enzymes: High affinity choline transporter 1
  3. Pathway

    Carbaryl Action Pathway

    smpdb.ca/view/SMP0126728
    Drug action

    Carbaryl is an insecticide in addition to a cholinesterase inhibitor it is used as a treatment to remove head lice. It acts on insects and due to its relative dosage compared to a human, the lice having their acetylcholinesterase inhibit...

    Drugs: Choline · Calcium · Magnesium cation · Acetylcholine · Acetic acid · Carbaryl
    Enzymes: High affinity choline transporter 1
  4. Pathway

    Methylphosphinic Acid Action Pathway

    smpdb.ca/view/SMP0126733
    Drug action

    Methylphosphinic acid is an experimental drug being tested to be a possible cholinesterase inhibitor, as it appears to inhibit the breakdown of acetylcholine. Further research needs to be conducted in order to confirm results, safety and...

    Drugs: Choline · Calcium · Magnesium cation · Methylphosphinic Acid · Acetylcholine · Acetic acid
    Enzymes: High affinity choline transporter 1
  5. Drug

    Somapacitan

    go.drugbank.com/drugs/DB15093
    ApprovedInvestigational

    [A219126,L15661] This human growth hormone analog differs by the creation of an albumin binding site, and prolonging the effect so that it requires weekly dosing rather than daily.

  6. Drug

    Butoconazole

    go.drugbank.com/drugs/DB00639
    Approved

    Butoconazole is an imidazole antifungal used in gynecology.

  7. Drug

    Azilsartan medoxomil

    go.drugbank.com/drugs/DB08822
    ApprovedInvestigational

    Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011. … As hypertension is a major risk factor for cardiovascular disease,[A7354] early management of hypertension has several implications on patients' survival rate and quality of life in the future.

  8. Drug

    Plicamycin

    go.drugbank.com/drugs/DB06810
    ApprovedWithdrawn

    Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus.

  9. Drug

    Enoxaparin

    go.drugbank.com/drugs/DB01225
    ApprovedInvestigational

    Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies.

  10. Drug

    Bardoxolone

    go.drugbank.com/drugs/DB12651
    Investigational

    It is a synthetic triterpenoid and a highly potent activator of redox-sensitive signaling pathways that induce programmed cell death (apoptosis) in cancer cells that are under high levels of intrinsic