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Displaying results 1321 - 1330 of 8970 in total
  1. Target

    Serine/threonine-protein kinase/endoribonuclease IRE1

    go.drugbank.com/bio_entities/BE0003839
    TargetHumans

    Acts as an upstream signal for ER stress-induced GORASP2-mediated unconventional (ER/Golgi-independent) trafficking of CFTR to cell membrane by modulating the expression and localization of SEC16A (PubMed … The endoribonuclease activity is specific for XBP1 mRNA and excises 26 nucleotides from XBP1 mRNA (PubMed:11779464, PubMed:21317875, PubMed:24508390).

    Synonyms: Endoplasmic reticulum-to-nucleus signaling 1
  2. Indication

    Aspiration Pneumonia

    go.drugbank.com/conditions/DBCOND0031880
    Drugs: Prednisolone
    Synonyms: Pneumonitis due to inhalation of food and vomit
  3. Indication

    Influenza Type B

    go.drugbank.com/conditions/DBCOND0041710
    Drugs: Oseltamivir
    Synonyms: Influenza due to other identified influenza virus
  4. Indication

    Urticaria Cold

    go.drugbank.com/conditions/DBCOND0162077
    Drugs: Cyproheptadine
    Synonyms: Urticaria due to cold (disorder)
  5. Drug

    Oxaloacetic acid

    go.drugbank.com/drugs/DB16921
    Investigational

    Synonyms: Oxalacetic acid trans-(z)-enol form
  6. Indication

    Diabetic Ketoacidosis

    go.drugbank.com/conditions/DBCOND0000979
    Drugs: Insulin aspart · Insulin lispro · Somatostatin
    Synonyms: Ketoacidosis due to diabetes mellitus, Ketoacidosis due to diabetes mellitus (disorder)
  7. Drug

    Sulfamethoxazole

    go.drugbank.com/drugs/DB01015
    ApprovedInvestigational

    in the biosynthesis of nucleic acids and proteins which are necessary for bacterial growth and division, and using them in conjunction helps to slow the development of bacterial resistance. … [L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps

    Mixtures: KEMOPRİM FORT 800/160 TABLET, SEPTRIN FORT TABLET, 20 ADETCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  8. Indication

    Blood Transfusion Complications

    go.drugbank.com/conditions/DBCOND0086922
    Drugs: Chlorpheniramine · Methylprednisolone · Triamcinolone
    Synonyms: Circulatory overload due to transfusion, Dyspnea due to and following transfusion
  9. Drug

    Eucalyptus oil

    go.drugbank.com/drugs/DB11114
    Approved

    Eucalyptus oil can be applied directly to the skin for pain and swelling of respiratory tract mucous membranes, joint pain, genital herpes, and nasal stuffiness. … It is also shown to exhibit antibacterial activity against some bacterial species and cough suppressant actions.

    Mixtures: Zam-Buk Ointment, Icy Hot No Mess Vapor Cough Suppresant for Kids
  10. Drug

    Bevantolol

    go.drugbank.com/drugs/DB01295
    Investigational

    Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. … Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.

    Products: BETA FORM