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Efbemalenograstim alfa
go.drugbank.com/drugs/DB18704ApprovedInvestigationalThis approval was contingent on positive results observed in two pivotal Phase 3 Studies GC-627-04 and GC-627-05 in the US and Europe respectively.[L48887] … Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration
Synonyms: Rh g-csf fc fusion protein f-627, Recombinant dimeric g-csf fusion protein f627Diroximel fumarate
go.drugbank.com/drugs/DB14783ApprovedInvestigational[A176474] It is the main cause of neurological disability not caused by trauma in the young adult population of both North America and Europe. … [A187535] Diroximel fumarate is a new drug from the fumarate class formulated to treat various relapsing forms of MS.
Iodine
go.drugbank.com/drugs/DB05382ApprovedInvestigationalAdditionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159] … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds.
Mixtures: Kordel"s Bio-Liquid Women"s Multi With Fish Oil Vegicap, Ni-C-E-LE PlusProducts: OQ SEPTIC ®, Varol 1% LiquidCilgavimab
go.drugbank.com/drugs/DB16393ApprovedInvestigationalSARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). … Certain SARS-CoV-2 Omicron subvariants may be associated with resistance to monoclonal antibodies, such as EVUSHELD.
Tixagevimab
go.drugbank.com/drugs/DB16394ApprovedInvestigationalSARS-CoV-2, the causative agent of COVID-19, enters cells via the interaction between the trimeric spike (S) glycoprotein and host cell angiotensin-converting enzyme 2 (ACE2). … Certain SARS-CoV-2 Omicron subvariants may be associated with resistance to monoclonal antibodies, such as EVUSHELD.
Simethicone
go.drugbank.com/drugs/DB09512ApprovedInvestigationalSimethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. … [A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308]
Mixtures: MUVETT S, MUVETT SCategories: Compounds used in a research, industrial, or household settingTauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawn[A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as a bile acid derivative. … Tauroursodeoxycholic acid can reduce the absorption of cholesterol in the small intestine, thereby reducing the body's intake of dietary cholesterol and the body cholesterol content.
Sulpiride Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126479Drug actionSulpiride is a substituted benzamide derivative and a selective dopamine D2 antagonist indicated to treat acute and chronic schizophrenia. Sulpiride is a selective dopamine D2 and D3 receptor antagonist.
Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortLoxapine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126481Drug actionLoxapine belongs to the class of first generation antipsychotics, a dibenzoxazepine compound in the subclass of tricyclic antipsychotic agents. Loxapine is a dopamine antagonist and serotonin 5-HT2 blocker.
Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortCaffeine Adrenergic A1 vasoconstriction Action Pathway
smpdb.ca/view/SMP0126537Drug actionCaffeine is a stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. The cardiovascular effects are extensive and can help with headaches, migraines, or other types of pain in certain ci...
Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short