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Displaying results 1341 - 1350 of 10000 in total
  1. Drug

    Naloxone

    go.drugbank.com/drugs/DB01183
    ApprovedInvestigationalVet approved

    [L33724] Naloxone is indicated for the rapid reversal of these symptoms of central nervous system depression in opioid overdose. … [L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use.

    Mixtures: TILIDIN HEXAL COMP D-PUMPE, TARGIN (R) 10 MG / 5 MG TABLETAS DE LIBERACIÓN PROLONGADACategories: Heterocyclic Compounds with 4 or More Rings, P-glycoprotein substrates
  2. Drug

    Ofranergene obadenovec

    go.drugbank.com/drugs/DB15175
    Investigational

    Ofranergene obadenovec is under investigation in clinical trial NCT01229865 (Safety and Efficacy of VB-111 in Subjects With Advanced Differentiated Thyroid Cancer).

    Synonyms: GENETIC VECTOR CONTAINING TUMOR VASCULAR ENDOTHELIUM-DIRECTED CHIMERIC FAS ANTIGEN GENE
  3. Drug

    Isopropyl alcohol

    go.drugbank.com/drugs/DB02325
    ApprovedInvestigational

    An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

    Mixtures: Prosera Soothing Hand Sanitizer, Anesthesia S/I-60Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Sodium tetradecyl sulfate

    go.drugbank.com/drugs/DB00464
    Approved

    An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Tetradecyl sulfate de sodium, 7-Ethyl-2-methyl-4-undecanol sulfate sodium salt
  5. Drug

    Turoctocog alfa

    go.drugbank.com/drugs/DB09109
    Approved

    Turoctocog alfa is produced in Chinese hamster ovary (CHO) cells without addition of any human- or animal-derived materials. … During secretion, some rFVIII molecules are cleaved at the C-terminal of the heavy chain (HC) at amino acid 720, and a monoclonal antibody binding C-terminal to this position is used in the purification

    Products: NOVOEIGHT®1000 UI POLVO Y SOLVENTE PARA SOLUCIÓN INYECTABLE, NOVOEIGHT® 250 UI POLVO Y SOLVENTE PARA SOLUCIÓN INYECTABLE
  6. Drug

    Iobenguane

    go.drugbank.com/drugs/DB06704
    ApprovedInvestigational

    Iodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008. … The radioisotope used can either be iodine-123 for imaging or iodine-131 for destruction of tissues that metabolize noradrenaline.

    Synonyms: 3-iodobenzylguanidine, m-iodobenzylguanidineSalts: Iobenguane I 123, Iobenguane I 131
  7. Indication

    Hyperkeratosis follicularis et parafollicularis

    go.drugbank.com/conditions/DBCOND0020027
    Drugs: Salicylic acid
    Synonyms: Hyperkeratosis follicularis in cutem penetrans (disorder), Keratosis follicularis et parafollicularis in cutem penetrans
  8. Drug

    Iloprost

    go.drugbank.com/drugs/DB01088
    ApprovedInvestigational

    Iloprost is an analog of prostacyclin (PGI2; epoprostenol), an endogenous prostanoid mainly produced in the vascular endothelium. It is more stable than prostacyclin, which is short-lived. … [A263326] Iloprost consists of a mixture of the 4R and 4S diastereoisomers at a ratio of approximately 53:47.[L50146] It is a potent vasodilator with reported anti-thrombotic properties.

    Synonyms: (5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid, (E)-(3aS, 4R, 5R, 6aS)-hexahydro-5-hydroxy-4-[(E)-(3S,4RS)­ 3-hydroxy-4-methyl-1-octen-6-ynyl]-Δ2(1H),Δ-pentalenevaleric acidProducts: İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL, İVİLOST 20 MCG/2 ML İV İNFÜZYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 5 AMPUL
  9. Drug

    Succimer

    go.drugbank.com/drugs/DB00566
    ApprovedInvestigational

    A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: DIM-SA, DMS-A
  10. Drug

    Edetate calcium disodium anhydrous

    go.drugbank.com/drugs/DB14598
    ApprovedInvestigational

    [L12774] It is on the World Health Organization Model List of Essential Medicines.[A204173] Edetate calcium disodium was granted FDA approval on 16 July 1953.[L12774] … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body.

    Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 CYP3A InhibitorsProducts: Calcium Edetate de Sodium