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Displaying results 1361 - 1370 of 10000 in total
  1. Drug

    Chromium picolinate

    go.drugbank.com/drugs/DB11255
    Approved

    Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. … Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss.

    Mixtures: RE FAC-x, BLACKMORES teen multi for GUYS capsuleCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  2. Drug

    Tianeptine

    go.drugbank.com/drugs/DB09289
    Investigational

    Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) [A31983]. … Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants [A31969].

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 Substrates
  3. Drug

    Efavirenz

    go.drugbank.com/drugs/DB00625
    ApprovedInvestigational

    For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen. … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human

    Mixtures: TOLAK ®3 TABLETAS RECUBIERTAS, TOLAK ®3 TABLETAS RECUBIERTASCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  4. Drug

    Brexucabtagene autoleucel

    go.drugbank.com/drugs/DB15699
    ApprovedInvestigational

    [A216153, A216158] More recently, chimeric antigen receptor (CAR) T cell therapies have been developed that modify a patient's own T cells using viral transduction to bind to and destroy cancerous cells … tumour cells in the CAR T cell preparation.

    Categories: Antineoplastic cell and gene therapy, Receptors, Antigen, T-Cell
  5. Drug

    Vusolimogene oderparepvec

    go.drugbank.com/drugs/DB23008
    ApprovedInvestigational

    on a PD-1-blocking antibody-based regimen. … on anti-PD-1 therapy.

    Categories: Antineoplastic cell and gene therapySynonyms: Hsv-1 oncolytic viral strain rp1
  6. Indication

    Phenylketonuria (PKU)

    go.drugbank.com/conditions/DBCOND0058086
    Drugs: Pegvaliase
    Synonyms: PAH-gene related phenylketonuria
  7. Drug

    Tetryzoline

    go.drugbank.com/drugs/DB06764
    Approved

    [A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several cases of drug-facilitated sexual assault.[A231764] … [A231769] Available since the 1950s, tetryzoline is a selective α<sub>1</sub>-receptor agonist [A231774] that is used as an ocular and nasal decongestant.

    Mixtures: FLU-SURE T® SUSPENSIÓN OFTÁLMICA, ISCHEMOL ACategories: Adrenergic alpha-1 Receptor Agonists, Heterocyclic Compounds, 1-Ring
  8. Drug

    Trifarotene

    go.drugbank.com/drugs/DB12808
    ApprovedInvestigational

    to vitamin A and are analogous only in function. … [L9013] Retinoids are a class of medications structurally and functionally analogous to [vitamin A], though later generation retinoids such as trifarotene and [adapalene] bear little structural resemblance

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: AKLIEF CREAM 50MCG/G
  9. Drug

    Dofetilide

    go.drugbank.com/drugs/DB00204
    ApprovedInvestigational

    Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation

    Synonyms: beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidideCategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 Substrates
  10. Drug

    Thimerosal

    go.drugbank.com/drugs/DB11590
    Approved

    Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes vaccines. … There has been significant concern regarding its safety and toxicity in the last several decades.

    Synonyms: ethyl(2-mercaptobenzoato-S)mercury sodium salt, [(o-carboxyphenyl)thio]ethylmercury sodium saltCategories: Compounds used in a research, industrial, or household setting