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Stem bromelain
go.drugbank.com/drugs/DB12249ApprovedThis action allows bromelain to demonstrate a wide range of therapeutic benefits ranging from cardiovascular to anticancer therapy - but the specific mechanisms of action by which it can elicit these effects … Bromelain is consequently a composite mixture of several different endopeptidases that can facilitate many different reactions with many different substrates.
Yellow fever vaccine
go.drugbank.com/drugs/DB10805ApprovedInvestigationalIt is composed of two live, attenuated strains of yellow fever virus, 17D-204 and 17DD, which have been shown to elicit an immune response identical to that induced by wild-type infection [FDA Label, A32118 … Yellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a _flavivirus_ through the bite of an infected mosquito.
Synonyms: Yellow fever virus live antigen, AProducts: STAMARIL 0,5 ML IM/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON VE ÇÖZÜCÜ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, STAMARIL ®Bepotastine
go.drugbank.com/drugs/DB04890ApprovedBepotastine was approved in Japan for use in the treatment of allergic rhinitis and uriticaria/puritus in July 2000 and January 2002, respectively, and is marketed by Tanabe Seiyaku Co., Ltd. under the … Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor.
Categories: Heterocyclic Compounds, 1-RingProducts: DOLCETTINA®Lymecycline
go.drugbank.com/drugs/DB00256ApprovedInvestigationalWithdrawnIt is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. … Lymecycline is not marketed in the USA, however, equivalent drugs are available, such as minocycline and [tetracycline].[A19429,L13880]
Synonyms: N-Lysinomethyltetracycline, N2-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracyclineProducts: XELTETRA-L, TETRALYSAL® CAPSULAS 300 MGElasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigationalFor the 2024-2025 season, an updated formulation was approved for use in Canada and the US to target the Omicron KP.2 subvariant.[L51404,L40074] … [L28026] On December 18, 2020, the FDA first issued an emergency use authorization (EUA) for the Moderna COVID-19 Vaccine as the second vaccine for the prevention of COVID-19 caused by SARS-CoV-2 in
Synonyms: MRNA-1273 SARS-COV-2Mixtures: Spikevax Bivalent (original / Omicron Ba.4/5)Eliglustat
go.drugbank.com/drugs/DB09039ApprovedInvestigational[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide. … [L41404,A7634] Eliglustat was approved by the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 Gaucher disease.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamideCytochrome b-c1 complex subunit 1, mitochondrial
go.drugbank.com/bio_entities/BE0001005TargetHumansComponent of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit...
Synonyms: Core protein IInterleukin-5
go.drugbank.com/bio_entities/BE0001208TargetHumansHomodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:2653458, PubMed:9010276). Also acts on activated and resting ...
Synonyms: B-cell differentiation factor ITestosterone cypionate
go.drugbank.com/drugs/DB13943ApprovedInvestigationalIt was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979. … Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: .- Im 100mg/mlInavolisib
go.drugbank.com/drugs/DB15275ApprovedInvestigationalInavolisib is an inhibitor of PI3Kα that was approved by the FDA in October 2024 for the treatment of certain patients with advanced breast cancers. … [A264563] Chemotherapeutic agents targeting the PI3K p110α catalytic subunit have shown antitumor activity and a manageable safety profile - some of which are in clinical use, like [alpelisib] - but preclinical
Categories: Cytochrome P-450 CYP2B6 Inducers, Heterocyclic Compounds, 1-RingSynonyms: (2S)-2-((2-((4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl)-5,6-dihydroimidazo(1,2-D)(1,4)benzoxazepin-9-yl)amino)propanamide, propanamide, 2-((2-((4S)-4-(difluoromethyl)-2-oxo-3-oxazolidinyl)-5,6-dihydroimidazo(1,2-D)(1,4)benzoxazepin-9-yl)amino)-, (2S)-