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Prednisolone acetate
go.drugbank.com/drugs/DB15566ApprovedInvestigationalVet approvedPrednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Mixtures: CONJUNTIN-S® LIQUIFILM® SUSPENSION OFTALMICA ESTERIL, PREFOX-T®Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesMagnesium chloride
go.drugbank.com/drugs/DB09407ApprovedInvestigationalMagnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.
Mixtures: B S S STERILE IRRIGATING SOLUTION, Isolyte SNoscapine
go.drugbank.com/drugs/DB06174ApprovedMixtures: TONIN COUGH SYRUP S, NEUMOLEX® NFCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP2C9 InhibitorsElasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigationalThe Moderna COVID-19 Vaccine (mRNA-1273; Elasomeran) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe … [L28026] A phase I, open-label, dose-ranging clinical trial (NCT04283461) was initiated in March 2020 in which 45 subjects received two intramuscular doses (on days 1 and 29).
Mixtures: Spikevax Bivalent (original / Omicron Ba.4/5)Synonyms: MRNA-1273 SARS-COV-2Fidanacogene elaparvovec
go.drugbank.com/drugs/DB16783ApprovedInvestigational[L49469] This approval was based on positive results demonstrated in the open-label, single-arm Phase 3 BENEGENE-2 study, where the annualized bleeding rate (ABR) was observed to be 1.3 for the 12 months … Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human coagulation FIX gene that was investigated as a potential treatment for hemophilia B.
Dicyclomine
go.drugbank.com/drugs/DB00804ApprovedInvestigational[A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small amount of evidence and so its prescription is becoming less favourable. … Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder
Mixtures: AXCEL DICYCLOMINE-S SYRUPSynonyms: 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate, Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl esterBetaine
go.drugbank.com/drugs/DB06756ApprovedInvestigationalNutraceuticalBetaine is a methyl group donor that functions in the normal metabolic cycle of methionine. … It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.
Mixtures: KORDEL`S NUTRITIME TABLET, Ultr F/b E.S. Mega Lipotropic Fmla W B6betSynonyms: 2-N,N,N-trimethylammonio acetate, N,N,N-TrimethylglycineSorbitol
go.drugbank.com/drugs/DB01638ApprovedInvestigationalIt was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. … A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose.
Mixtures: MINICA S ENEMA, Cystosol W 3% HexitolsCategories: Compounds used in a research, industrial, or household settingSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigationalSimvastatin, also known as the brand name product Zocor, is a lipid-lowering drug derived synthetically from a fermentation product of _Aspergillus terreus_. … as well as the need for surgical revascularization or angioplasty following a heart attack.
Mixtures: TIAZOMET S®, TIAZOMET S®Categories: P-glycoprotein inhibitors, P-glycoprotein substratesPhenserine
go.drugbank.com/drugs/DB04892InvestigationalIf this is substantiated in an ongoing clinical trial then phenserine may open the door to an entirely new type of treatment for AD. … Phenserine is under development by Axonyx, a US biopharmaceutical company that focuses on treatments for dementia.
Categories: Heterocyclic Compounds, 2-Ring