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Displaying results 1361 - 1370 of 10000 in total
  1. Drug

    Aluminum chloride

    go.drugbank.com/drugs/DB11081
    ApprovedInvestigational

    It is used in various chemical applications as a Lewis base, with anhydrous aluminium trichloride being the most commonly used Lewis acid. … In antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15%, calculated on the hexahydrate form, in an aqueous solution nonaerosol dosage form [L2012].

    Products: Gingi Aid 10%, Ms Hemostatic
  2. Drug

    Canagliflozin

    go.drugbank.com/drugs/DB08907
    ApprovedInvestigational

    Canagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise … 2 diabetes mellitus [L5897], [FDA label].

    Mixtures: VOKANAMET 50 MG/500 MG, VOKANAMET 50 MG/850 MG FİLM KAPLI TABLET, 60 ADETCategories: Heterocyclic Compounds, 1-Ring, Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors
  3. Drug

    Naphazoline

    go.drugbank.com/drugs/DB06711
    Approved

    Naphazoline was first developed in 1942 as a nasal formulation for congestion[A176609].

    Mixtures: SULFARHIN BURUN MERHEMI, 20 G, SULFARHIN BURUN MERHEMI, 12 GCategories: Adrenergic alpha-2 Receptor Agonists, Sympathomimetics Used as Decongestants
  4. Drug

    Ciprofibrate

    go.drugbank.com/drugs/DB09064
    ApprovedInvestigationalWithdrawn

    Products: MODALIM TABLET 100 mg, CIPROFIBRATO 100 MG TABLETAS
  5. Drug

    Tucatinib

    go.drugbank.com/drugs/DB11652
    ApprovedInvestigational

    It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. … Tucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable or metastatic HER-2 positive breast cancer.

    Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: TUKYSA 50 mg film-coated tablets, TUKYSA (TUCATINIB) FILM-COATED TABLETS 50 mg
  6. Drug

    Ipilimumab

    go.drugbank.com/drugs/DB06186
    ApprovedInvestigational

    [A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex.[L12126] Ipilimumab was granted FDA approval on 25 March 2011.[L12126]

    Categories: Immunoglobulin GProducts: YERVOY 5 mg/ml concentrate for solution for infusion, YERVOY®5 MG /ML SOLUCION INYECTABLE PARA INFUSION INTRAVENOSA
  7. Drug

    Aluminum acetate

    go.drugbank.com/drugs/DB14518
    ApprovedInvestigational

    Products: ACETATO DE ALUMINIO 15 MG/100 ML SOLUCION TOPICA, ACETATO DE ALUMINIO 0.118G/100 ML
  8. Target

    3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase

    go.drugbank.com/bio_entities/BE0001679
    TargetMycobacterium tuberculosis

    Probably involved in steroid metabolism. Catalyzes the oxidation of androsterone (3alpha-hydroxy-5alpha-androstan-17-one) and 20beta-hydroxyprogesterone (4-pregnen-20beta-ol-3-one), and the reduction of progesterone (4-pregnen-3,20-dione...

    Polypeptides: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
  9. Target

    tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

    go.drugbank.com/bio_entities/BE0020091
    EnzymeHumans

    Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:15994936, PubMed:26429968, PubMed:30149704, PubMed:34798057, PubMed:38680565).

    Polypeptides: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
  10. Drug

    Magnesium chloride

    go.drugbank.com/drugs/DB09407
    ApprovedInvestigational

    Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

    Mixtures: Aminosyn II 8.5% M In 20% Dextrose (dual Chamber), Gelofusin Iso 40 mg/ml InfusionslösungProducts: Slow-mag, Slow-mag-tab