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Voxilaprevir
go.drugbank.com/drugs/DB12026ApprovedInvestigationalPrior to Vosevi, there were no approved retreatment options for patients who have previously received, and failed, a regimen containing an NS5A inhibitor for treatment of chronic HCV infection. … with an HCV regimen containing sofosbuvir without an NS5A inhibitor [L935].
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseMoxidectin
go.drugbank.com/drugs/DB11431ApprovedInvestigationalVet approved[A33385] Moxidectin was developed by Medicines Development for Global Health and FDA approved in June 13, 2018.[L2970] … It was first used in cattle followed by an approved use in general animals. It is a semi-synthetic methoxine derivative of nemadectin which is a 16-member pentacyclic lactone of the milbemycin class.
Mixtures: Advocate Spot-on Solution for Small Dogs, Advocate Spot-on Solution for Large DogsPafolacianine
go.drugbank.com/drugs/DB15413ApprovedInvestigational[A242572] On November 29, 2021, the FDA approved pafolacianine as an adjunct imaging agent for intraoperative identification of malignant lesions in adult patients with ovarian cancer. … [L39332] The longer wavelength allows for deeper penetration of the fluorescent light through tissues for better imaging and detection of tumours.
Imatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigationalThe discovery of imatinib also established a new group of therapy called "targeted therapy", since treatment can be tailored specifically to the unique cancer genetics of each patient.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidideGeneralized tonic-clonic Seizures
go.drugbank.com/conditions/DBCOND0050096Synonyms: Grand mal, Grand mal fitEstrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast Cancer
go.drugbank.com/conditions/DBCOND0111347Drugs: VepdegestrantSynonyms: Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast CancerSodium lauryl sulfate
go.drugbank.com/drugs/DB00815ApprovedSodium Lauryl Sulfate (SLS) is an anionic surfactant naturally derived from coconut and/or palm kernel oil. It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl.
Mixtures: For Sope, Trimo SanIodide I-123
go.drugbank.com/drugs/DB09420ApprovedInvestigationalRadioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h (hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared … Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease.
Defibrotide
go.drugbank.com/drugs/DB04932ApprovedInvestigationalDefibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from porcine mucosal DNA. It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without associated s...
Indigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigationalThis compound is an acid-base indicator and is used in the production of food colorants and pH tests.
Categories: Tests for Renal Function and Ureteral Injuries