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Displaying results 131 - 140 of 302 in total
  1. Target

    T-complex protein 1 subunit gamma

    go.drugbank.com/bio_entities/BE0004554
    TargetHumans

    As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638) … Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis (PubMed:25467444, PubMed:36493755

    Polypeptides: T-complex protein 1 subunit gammaSynonyms: Chaperonin containing T-complex polypeptide 1 subunit 3
  2. Target

    T-complex protein 1 subunit eta

    go.drugbank.com/bio_entities/BE0009220
    TargetPlasmodium falciparum (isolate 3D7)

    Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

    Polypeptides: T-complex protein 1 subunit eta
  3. Target

    H/ACA ribonucleoprotein complex subunit DKC1

    go.drugbank.com/bio_entities/BE0012026
    TargetHumans

    Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA (PubMed:25219674, PubMed:32554502).

    Polypeptides: H/ACA ribonucleoprotein complex subunit DKC1
  4. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    It will compare pixantrone efficacy to that of gemcitabine. [2]

  5. Indication

    Algodystrophy

    go.drugbank.com/conditions/DBCOND0034820
    Drugs: Neridronic Acid
    Synonyms: Complex regional pain syndrome type I, Complex regional pain syndrome
  6. Target

    Vitamin K epoxide reductase complex subunit 1

    go.drugbank.com/bio_entities/BE0000713
    TargetEnzymeHumans

    Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K.

    Polypeptides: Vitamin K epoxide reductase complex subunit 1
  7. Target

    H subunit of photosynthetic reaction center complex

    go.drugbank.com/bio_entities/BE0003883
    TargetThermochromatium tepidum

    Polypeptides: H subunit of photosynthetic reaction center complex
  8. Target

    ATP synthase F(0) complex subunit a

    go.drugbank.com/bio_entities/BE0009014
    TargetHumans

    ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit a, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated

    Polypeptides: ATP synthase F(0) complex subunit aSynonyms: Proton-conducting channel, ATP synthase F(0) complex subunit a
  9. Target

    Target of rapamycin complex 2 subunit MAPKAP1

    go.drugbank.com/bio_entities/BE0018900
    TargetHumans

    Inhibits HRAS and KRAS independently of mTORC2 complex (PubMed:17303383, PubMed:34380736, PubMed:35522713). … Involved in ciliogenesis, regulates cilia length through its interaction with CCDC28B independently of mTORC2 complex (PubMed:23727834)

    Polypeptides: Target of rapamycin complex 2 subunit MAPKAP1
  10. Target

    Integrase, catalytic core

    go.drugbank.com/bio_entities/BE0003386
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Integrase, catalytic core