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Displaying results 1391 - 1400 of 10000 in total
  1. Drug

    Dapsone

    go.drugbank.com/drugs/DB00250
    ApprovedInvestigational

    A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8)

    Synonyms: 4-(4-aminophenylsulfonyl)aniline, p,p-sulphonylbisbenzamineMixtures: Dapsone 6% / Niacinamide 2% / Spironolactone 5%, Dapsone 8.5% / Niacinamide 2% / Spironolactone 5%
  2. Drug

    Temuterkib

    go.drugbank.com/drugs/DB18806
    Investigational

    Synonyms: 4h-thieno(2,3-c)pyrrol-4-one, 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl)-5-(2-(4-morpholinyl)ethyl)-, 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl)-5-(2-(4-morpholinyl)ethyl)-4h-thieno(2,3-c)pyrrol-4-oneCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Isuzinaxib

    go.drugbank.com/drugs/DB19109
    Investigational

    Isuzinaxib is under investigation in clinical trial NCT05758896 (Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI).

    Synonyms: 1-(pyridin-2-yl)-3-phenyl-4-propyl-1h-pyrazol-5-ol, 3-phenyl-4-propyl-1-(2-pyridinyl)-1h-pyrazol-5-olCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Levetiracetam

    go.drugbank.com/drugs/DB01202
    ApprovedInvestigational

    make it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions. … Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: LEVEBRAIN 100MG/ML ORAL ÇÖZELTI,5 ML ENJEKTÖR+150 ML, KEPPRA 100 MG/ML ORAL COZELTI, 150 ML + 3 ENJEKTOR
  5. Drug

    Ribavirin elaidate

    go.drugbank.com/drugs/DB17193
    Experimental

    Synonyms: 1h-1,2,4-triazole-3-carboxamide, 1-(5-o-((9e)-1-oxo-9-octadecen-1-yl)-.beta.-d-ribofuranosyl)-, Ribavirin-5'-elaidic acid ester
  6. Drug

    Cemdomespib

    go.drugbank.com/drugs/DB18953
    Investigational

    Cemdomespib is under investigation in clinical trial NCT05895552 (A Phase 2 Study of RTA 901 in Patients With Diabetic Peripheral Neuropathic Pain (CYPRESS)).

    Synonyms: Acetamide, n-(2-(5-((6-deoxy-5-c-methyl-4-o-methyl-.alpha.-l-lyxo-hexopyranosyl)oxy)-3'-fluoro(1,1'-biphenyl)-2-yl)ethyl)-
  7. Drug

    Dethiobiotin

    go.drugbank.com/drugs/DB03775
    Experimental

    Synonyms: (4R,5S)-5-methyl-2-oxo-4-imidazolidinehexanoic acid, (4R-cis)-5-methyl-2-oxo-4-imidazolidinehexanoic acidCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Pseudoephedrine

    go.drugbank.com/drugs/DB00852
    Approved

    Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system. … [A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.

    Synonyms: d-psi-2-Methylamino-1-phenyl-1-propanol, (+) threo-2-(methylamino)-1-phenyl-1-propanolInternational brands: Eltor 120
  9. Drug

    Ivabradine

    go.drugbank.com/drugs/DB09083
    ApprovedInvestigational

    Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate … ≥70 beats per minute, who are not on beta-blockers due to contraindications or already receiving maximum beta-blocker dose.

    Mixtures: Implicor 50 mg/5 mg Filmtabletten, IMPLICOR FILM-COATED TABLET 50 mg/5 mgCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Novobiocin

    go.drugbank.com/drugs/DB01051
    ApprovedInvestigationalVet approvedWithdrawn

    It has a chemical structure similar to coumarin. Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. … (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p189) Novobiocin sodium, a salt form of novobiocin, was initially approved in September 1964 and was indicated for the treatment of serious

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-β-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl}-4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamide