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Ropeginterferon alfa-2b
go.drugbank.com/drugs/DB15119ApprovedInvestigational[A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing and is not tolerated by all patients. … [A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from proline-IFN-α-2b in _Escherichia coli_ that has high tolerability and a long half-life.
Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: PEG-P-IFN-alfa-2b, PEG-P-IFN-alpha-2bLoxapine
go.drugbank.com/drugs/DB00408ApprovedInvestigationalAn antipsychotic agent used in schizophrenia. [PubChem]
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsSynonyms: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepineFruquintinib
go.drugbank.com/drugs/DB11679ApprovedInvestigationalFruquintinib is a novel small-molecule anti-VEGFR that targets VEGFR-1,-2, and -3 to inhibit angiogenesis. … The first approach can be exemplified by [bevacizumab], a VEGF-A trap antibody.
Categories: Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors, Cytochrome P-450 SubstratesGlisoxepide
go.drugbank.com/drugs/DB01289InvestigationalGlisoxepide uptake could be further inhibited by blockers of the hepatocellular monocarboxylate transporter, by the loop diuretic bumetanide, by 4,4'-diisothiocyano-2,2'-stilbenedisulfonate (DIDS) and
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesCentella asiatica
go.drugbank.com/drugs/DB14256ApprovedCentella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: Centella 65 Green Tea Pack, MADECASSOL CProducts: Madepair %1 Merhem, 40 g, MADECASSOL %1 MERHEM, 40 GAlbuterol
go.drugbank.com/drugs/DB01001ApprovedInvestigationalVet approvedThe R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer has been associated with toxicity. … Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD.
Mixtures: ULAX-C, UNIBRON RCategories: Adrenergic beta-2 Receptor Agonists, Cytochrome P-450 CYP3A InhibitorsGelatin
go.drugbank.com/drugs/DB11242ApprovedInvestigationalVet approvedWithdrawn[L2121] Fish skins from a number of fish species a type of substance that has been comprehensively studied as a source for gelatin production. … An increasing number of novel applications have been found for collagen and gelatin.[A32426] Gelatin is generally recognized as safe (GRAS) by the FDA to be a non-hazardous food or food ingredient.
Mixtures: GELOFUSINE® ISO 4%Products: INFUSOL SG (SUCCINYLATED GELATIN (Bovine) INTRAVENOUS INFUSION 4% w/v), GELAFUNDIN 4Tepotinib
go.drugbank.com/drugs/DB15133ApprovedInvestigationalTepotinib is a MET tyrosine kinase inhibitor intended to treat a variety of MET-overexpressing solid tumors. … Anderson Cancer Center in 2009 and has since been investigated in the treatment of neuroblastoma,[A228053] gastric cancers,[A228033] non-small cell lung cancer, and hepatocellular carcinoma.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsChlorcyclizine
go.drugbank.com/drugs/DB08936ApprovedChlorcyclizine is a first generation phenylpiperazine class antihistamine used to treat urticaria, rhinitis, pruritus, and other allergy symptoms.
Mixtures: Statuss Green, biclora-DCategories: Heterocyclic Compounds, 1-RingMagnesium citrate
go.drugbank.com/drugs/DB11110ApprovedInvestigationalMagnesium citrate is a low volume and osmotic cathartic agent. … [T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under the specifications of oral administration of a maximum concentration of 237 mg.
Mixtures: Q-10 Plus, Formula R TabProducts: BET-R-PREP Magnesium Citrate Oral