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Displaying results 1391 - 1400 of 10000 in total
  1. Drug

    Propanoic acid

    go.drugbank.com/drugs/DB03766
    ApprovedInvestigationalVet approvedWithdrawn

    Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals or a granular crystalline powder. … Sodium propionate was previously approved in Canada as an active ingredient in Amino-Cerv (used to treat inflammation or injury of the cervix).

  2. Drug

    Teplizumab

    go.drugbank.com/drugs/DB06606
    ApprovedInvestigational

    [L44096] In April 2026, the FDA approved an expanded indication for teplizumab, lowering the eligible age range from 8 years and older down to 1 year and older for patients with Stage 2 T1D.[L56140] … Teplizumab (teplizumab-mzwv) is a humanized IgG1 kappa CD3-directed monoclonal antibody used to delay the onset of type 1 diabetes (T1D).

    Categories: Drugs Used in DiabetesSynonyms: hOKT3 γ1(Ala-Ala), hOKT3 gamma1(Ala-Ala)
  3. Drug

    Tabelecleucel

    go.drugbank.com/drugs/DB17072
    ApprovedInvestigational

    [A253292,A253297,L43557] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended tabelecleucel be granted marketing authorization for the treatment of adult and … When given to a patient with EBV-associated post-transplant lymphoproliferative disorder (PTLD) following solid organ transplantation (SOT) or hematopoietic cell transplant, T-cells attack the patient's

  4. Drug

    Cabotegravir

    go.drugbank.com/drugs/DB11751
    ApprovedInvestigational

    [L31198] While previously administered once monthly only, this combination product was granted FDA approval for dosing every two months on February 01, 2022 [L40084] and without the need for an oral lead-in … formulation for cabotegravir.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseProducts: Apretude 600mg Prolonged-release suspension for injection
  5. Drug

    Retifanlimab

    go.drugbank.com/drugs/DB15766
    ApprovedInvestigational

    On October 2021, Incyte Biosciences withdrew its application for a marketing authorization of retifanlimab for the treatment of squamous carcinoma of the anal canal. … [L45608,L45618] On March 2023, the FDA granted accelerated approval to retifanlimab for a different indication, the treatment of metastatic or recurrent locally advanced Merkel cell carcinoma (MCC).

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors
  6. Drug

    Tropicamide

    go.drugbank.com/drugs/DB00809
    Approved

    [A230103] Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia for eye exams or ocular procedures. … [A229958] It is also used in combination with [hydroxyamphetamine] for the same indication.

  7. Drug

    Niclosamide

    go.drugbank.com/drugs/DB06803
    ApprovedInvestigationalVet approved

    Niclosamide is an antihelminthic used for the treatment of tapeworm infections. … Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases.

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Thiamylal

    go.drugbank.com/drugs/DB01154
    ApprovedVet approved

    A barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p919)

  9. Drug

    Varenicline

    go.drugbank.com/drugs/DB01273
    ApprovedInvestigational

    become aggressive or black out. … In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S.

    Categories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine Dependence
  10. Drug

    Fluoroestradiol F-18

    go.drugbank.com/drugs/DB15690
    ApprovedInvestigational

    across metastases (i.e. to identify sites that no longer express ER) without the need for multiple biopsies. … [L14096] The ability to image ER-positive tumors _in vivo_ is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression