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Displaying results 1421 - 1430 of 10000 in total
  1. Indication

    Predominant skin comedones, papules and pustules

    go.drugbank.com/conditions/DBCOND0106072
    Drugs: Erythromycin
    Synonyms: Predominant skin comedones, papules and pustules
  2. Drug

    Passiflora incarnata flower

    go.drugbank.com/drugs/DB13974
    Approved

    Mixtures: Herbal Sleep Aid, Zand Calming Herbal LiqCategories: Hypnotics and Sedatives, Herbs and Natural Products
  3. Drug

    Galsulfase

    go.drugbank.com/drugs/DB01279
    ApprovedInvestigational

    The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate manose7 oligosaccharide for specific cellular … Post-translational modification of Cys53 produces the catalytic amino acid residue Ca-formylglycine, which is required for enzyme activity and is conserved in all members of the sulfatase enzyme family

    Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismProducts: Naglazyme Concentrated Solution for Intravenous Infusion 1mg/1ml
  4. Drug

    Mebendazole

    go.drugbank.com/drugs/DB00643
    ApprovedInvestigationalVet approved

    A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]

    Categories: Antiparasitic Products, Insecticides and RepellentsProducts: PRIMEDAZOL TABLET 100MG, THELMOX TABLET 100MG
  5. Drug

    Cefprozil

    go.drugbank.com/drugs/DB01150
    ApprovedInvestigational

    Cefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.

    Products: Cefzil Tablets - 250mg, ZILCEF 250MG/5ML ORAL SÜSPANSIYON HAZIRLAMAK ICIN KURU TOZ ,100ML
  6. Drug

    Adalimumab

    go.drugbank.com/drugs/DB00051
    ApprovedInvestigational

    This drug is available in a prefilled syringe form and convenient pen form for subcutaneous self-administered doses.[A39983] Several biosimilars to adalimumab. … [A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA.[A39983] This drug is frequently known as _Humira_.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: HUMIRA SOLUTION FOR INJECTION 20MG/0.2ML (PRE-FILLED SYRINGE), HUMIRA Solution for Injection in Prefilled syringe 20MG/0.2ML
  7. Drug

    Dicloxacillin

    go.drugbank.com/drugs/DB00485
    ApprovedInvestigationalVet approved

    One of the penicillins which is resistant to penicillinase.

    Products: DICLOX SUSPENSION 250MG, DICLOXACILINA 250MG/5ML POLVO PARA RECONSTITUIR
  8. Drug

    Axitinib

    go.drugbank.com/drugs/DB06626
    ApprovedInvestigational

    [L6676] Axitinib is an indazole derivative.[A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. … [L6676] Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases.

    Categories: Benzamides and benzamide derivatives, Antineoplastic and Immunomodulating AgentsProducts: INLYTA TABLETS 1MG, Inlyta Film-coated Tablets 1mg
  9. Target

    NACHT, LRR and PYD domains-containing protein 3

    go.drugbank.com/bio_entities/BE0010347
    TargetHumans

    ATP released from necrotic cells triggers activation of NLRP3 inflammasome through P2RX7 signaling leading to neutrophil adhesion to the vascular endothelium close to the injury site (By similarity). … Recruitment of pro-caspase-1 (proCASP1) to the NLRP3 inflammasome promotes caspase-1 (CASP1) activation, which subsequently cleaves and activates inflammatory cytokines IL1B and IL18 and gasdermin-D (GSDMD

    Polypeptides: NACHT, LRR and PYD domains-containing protein 3
  10. Target

    Zinc finger and BTB domain-containing protein 7A

    go.drugbank.com/bio_entities/BE0012406
    TargetHumans

    Specifically represses the transcription of the tumor suppressor ARF isoform from the CDKN2A gene (By similarity). Efficiently abrogates E2F1-dependent CDKN2A transactivation (By similarity). … Directly and specifically binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3' and represses transcription both by regulating the organization of chromatin and through the direct recruitment of transcription

    Polypeptides: Zinc finger and BTB domain-containing protein 7ASynonyms: POZ and Krueppel erythroid myeloid ontogenic factor