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Azintuxizumab vedotin
go.drugbank.com/drugs/DB14847InvestigationalHas Come Back or Had No Response to Recent Cancer Treatment). … Azintuxizumab vedotin is under investigation in clinical trial NCT02951117 (A Study of Venetoclax and ABBV-838 Combination Therapy With Dexamethasone in Participants With Multiple Myeloma Whose Cancer
Doconexent
go.drugbank.com/drugs/DB03756ApprovedInvestigationalA mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. … It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin, and retina thus plays an important role in their development and function.
Mixtures: Protect Cardio AFPlumbagin
go.drugbank.com/drugs/DB17048InvestigationalPlumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]
Categories: Compounds used in a research, industrial, or household settingCarbidopa
go.drugbank.com/drugs/DB00190ApprovedInvestigationalCarbidopa presents a chemical denomination of N-amino-alpha-methyl-3-hydroxy-L-tyrosine monohydrate. … An individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea.
Mixtures: Ag-levocarb, Ag-levocarbChlorphentermine
go.drugbank.com/drugs/DB01556ApprovedIllicitWithdrawnA sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension.
Synonyms: 4-Chloro-a,a-dimethylbenzeneethanamine, 4-Chloro-a,a-dimethylphenethylamineFostemsavir
go.drugbank.com/drugs/DB11796ApprovedInvestigational[L14867] The discovery of gp120 as a potential target of interest in the treatment of HIV-1 infection is relatively recent, and was born out of a desire to find alternative target proteins (i.e. mechanistically … Fostemsavir is the phosphonooxymethyl prodrug of temsavir, a novel HIV-1 attachment inhibitor.
Omega-3 fatty acids
go.drugbank.com/drugs/DB11133ApprovedInvestigationalNutraceuticalOmega-3 fatty acids are polyunsaturated fatty acids (PUFAs) with a double bond at the third carbon atom from the end of the carbon chain. … Omega-3 fatty acids play a critical role in metabolism and cellular function and they are available as daily supplements. On September 8, 2004, the U.S.
Mixtures: Advanced AM PMVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalSpecifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. … Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist.
Categories: Cholinergic Receptor AgonistPromazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnA phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.
Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin Receptor Antagonists