Search

Displaying results 1471 - 1480 of 2744 in total
  1. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

    go.drugbank.com/bio_entities/BE0000191
    TargetEnzymeHumans

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor … Essential for the catalytic activity and assembly of complex I (PubMed:14729820, PubMed:24028823, PubMed:30140060)

    Synonyms: Complex I-30kD
  2. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

    go.drugbank.com/bio_entities/BE0000729
    TargetEnzymeHumans

    Essential for the catalytic activity of complex I (PubMed:22036843, PubMed:30922174). Essential for the assembly of complex I (By similarity). … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-49kD
  3. Target

    Protein SLC31A2

    go.drugbank.com/bio_entities/BE0003662
    TransporterHumans

    export and modulates the copper and cisplatin accumulation via SLC31A1 (By similarity) … Does not function as a copper(1+) importer in vivo (By similarity). However, in vitro functions as a low-affinity copper(1+) importer (PubMed:17617060, PubMed:17944601).

    Synonyms: Copper transporter 2Function: copper ion transmembrane transporter activity
  4. Drug

    Ethoxzolamide

    go.drugbank.com/drugs/DB00311
    ApprovedWithdrawn

    Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. Its pharmacological activity thus confe...

    Categories: Genito Urinary System and Sex Hormones
  5. Drug

    Sertaconazole

    go.drugbank.com/drugs/DB01153
    Approved

    Sertaconazole nitrate is an antifungal medication of the imidazole class. It is available in topical formulations for the treatment of skin infections such as athlete's foot.

    Categories: Genito Urinary System and Sex Hormones
  6. Drug

    Isoconazole

    go.drugbank.com/drugs/DB08943
    Approved

    Isoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.

    Categories: Genito Urinary System and Sex Hormones
  7. Drug

    Ammonium chloride

    go.drugbank.com/drugs/DB06767
    ApprovedInvestigationalVet approved

    Ammonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.

    Categories: Genito Urinary System and Sex Hormones
  8. Drug

    Afacifenacin

    go.drugbank.com/drugs/DB21385
    Experimental

    The usage of the INN stem '-fenacin' in the name indicates that Afacifenacin is a muscarinic receptor antagonist. Afacifenacin has a monoisotopic molecular weight of 481.2 Da.

  9. Drug

    Fosifidancitinib

    go.drugbank.com/drugs/DB21462
    Experimental

    The usage of the INN stem '-citinib' in the name indicates that Fosifidancitinib is a Janus kinase inhibitor. Fosifidancitinib has a monoisotopic molecular weight of 505.12 Da.

  10. Drug

    Gemnelatinib

    go.drugbank.com/drugs/DB21513
    Experimental

    The usage of the INN stem '-tinib' in the name indicates that Gemnelatinib is a tyrosine kinase inhibitor. Gemnelatinib has a monoisotopic molecular weight of 524.23 Da.