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Displaying results 1481 - 1490 of 10000 in total
  1. Drug

    Quinidine

    go.drugbank.com/drugs/DB00908
    Approved

    [A38016] It prolongs cellular action potential by blocking sodium and potassium currents. … A phenomenon known as “quinidine syncope” was first described in the 1950s, characterized by syncopal attacks and ventricular fibrillation in patients treated with this drug.

    Mixtures: Dextromethorphan hydrobromide and quinidine sulfate, Dextromethorphan Hydrobromide and Quinidine SulphateCategories: Quinine and stereoisomer, Metabolic Side Effects of Drugs and Substances
  2. Target

    Sensor cyclic diguanylate phosphodiesterase, GAF and GAF domain-containing

    go.drugbank.com/bio_entities/BE0004305
    TargetGeobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)

    Polypeptides: Sensor cyclic diguanylate phosphodiesterase, GAF and GAF domain-containing
  3. Target

    Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

    go.drugbank.com/bio_entities/BE0009519
    TargetHumans

    May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect (PubMed:9001210, PubMed:9268380)

    Polypeptides: Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
  4. Target

    Signal transducer and activator of transcription 1-alpha/beta

    go.drugbank.com/bio_entities/BE0010099
    TargetHumans

    and STAT2. … Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors (PubMed:12764129, PubMed:12855578,

    Polypeptides: Signal transducer and activator of transcription 1-alpha/beta
  5. Indication

    Acute naused and vomiting caused by Chemotherapy

    go.drugbank.com/conditions/DBCOND0025637
    Drugs: Netupitant · Palonosetron
    Synonyms: Acute Chemotherapy-Induced Nausea and Vomiting, Acute chemotherapy induced nausea and vomiting
  6. Indication

    Non-complicated Skin and Soft Tissue Infections

    go.drugbank.com/conditions/DBCOND0046572
    Drugs: Teicoplanin
    Synonyms: Non-complicated Skin and Soft Tissue Infections
  7. Indication

    Other and unspecified effects of high altitude

    go.drugbank.com/conditions/DBCOND0024755
    Drugs: Acetazolamide
    Synonyms: Other and unspecified high altitude effects, Other and unspecified effects of high altitude
  8. Indication

    Complicated Skin and subcutaneous tissue bacterial infection

    go.drugbank.com/conditions/DBCOND0025759
    Drugs: Dalfopristin · Quinupristin · Telavancin
    Synonyms: Complicated skin and subcutaneous tissue bacterial infections, Complicated Skin and subcutaneous tissue bacterial infection
  9. Drug

    Tacrolimus

    go.drugbank.com/drugs/DB00864
    ApprovedInvestigational

    Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. … It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide.

    Categories: Skin and Mucous Membrane Agents, Antineoplastic and Immunomodulating AgentsProducts: PROGRAF CAPSULE 1MG, TACROCORD 1 CAPSULES 1MG
  10. Drug

    Glucagon

    go.drugbank.com/drugs/DB00040
    ApprovedInvestigational

    Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia. … [L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.

    Categories: Sex Hormones and Insulins, Amino Acids, Peptides, and ProteinsProducts: GLUCAGEN 1MG INJECTION, Glucagon Ampoule 666 1mg