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Dapsone
go.drugbank.com/drugs/DB00250ApprovedInvestigationalIt is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8) … Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms.
Products: DAPSULON® 50 MG, Dapsone 25 mgEncorafenib
go.drugbank.com/drugs/DB11718ApprovedInvestigationalMutations in this gene, most frequently the V600E mutation, are the most commonly identified cancer-causing mutations in melanoma, and have been isolated in various other cancers as well, including non-Hodgkin … melanoma with a BRAF V600E or V600K mutation, as detected by an FDA-approved test.
Products: BRAFTOVI® 75 MG CÁPSULAS, BRAFTOVİ 75 MG SERT KAPSÜL, 42 ADETTioguanine
go.drugbank.com/drugs/DB00352ApprovedInvestigationalAn antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Synonyms: TG, 6-TGProducts: THIOGUANINE TABLETAS 40 MG, Thioguanin "Aspen" 40 mg TablettenLymecycline
go.drugbank.com/drugs/DB00256ApprovedInvestigationalWithdrawn[A203255] Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. … Lymecycline is not marketed in the USA, however, equivalent drugs are available, such as minocycline and [tetracycline].[A19429,L13880]
Synonyms: N-Lysinomethyltetracycline, (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamideProducts: CycloPel 300 mg Kapseln, TETRALYSAL® CAPSULAS 300 MGIsavuconazonium
go.drugbank.com/drugs/DB06636ApprovedInvestigational[A6913,A6914,A262706] On December 08, 2023, the FDA approved the expanded use of isovuconazonium in pediatric patients for the same indications.[L49251] … Due to low solubility in water of isavuconazole on its own, the isovuconazonium formulation is favorable as it has high solubility in water and allows for intravenous administration.
Products: CRESEMBA® 200 MG POLVO LIOFILIZADO ESTERIL PARA RECONSTITUIRUrea
go.drugbank.com/drugs/DB03904ApprovedInvestigationalIt is the principal end product of protein catabolism and constitutes about one half of the total urinary solids. … A compound formed in the liver from ammonia produced by the deamination of amino acids.
Mixtures: HYDROCORTISONE 1% ET UREA 5% CREAM, ÜRESAL FORTE %10 + %10 MERHEM (50 G)Products: UBIT TABLET 100 MG, EUREA CREAMLevamlodipine
go.drugbank.com/drugs/DB09237ApprovedInvestigational[A188940] Levamlodipine was granted FDA approval on 19 December 2019.[L10833] … [L10833] This medication was first marketed in Russia and India before being granted FDA approval.
Mixtures: VOLTRAMOS 2.5 MG/160 MG FILM KAPLI TABLET, 28 ADET, VOLTRAMOS 5 MG/160 MG FILM KAPLI TABLET, 28 ADETProducts: ALENCAL®2.5 MGApalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalIn a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant prostate cancer had ≥50% PSA decline at week 12 of apalutamide treatment [A31846]. … In a randomized trial, the median metastasis-free survival for patients taking apalutamide was 40.5 months compared to 16.2 months for patients taking a placebo [L1295].
Products: ERLEADA ®TABLETAS RECUBIERTAS 60 MGNonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnN-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants. … It is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market.
Categories: Compounds used in a research, industrial, or household settingProducts: OKSİNOL 150 MG OVÜLClofazimine
go.drugbank.com/drugs/DB00845ApprovedInvestigationalWithdrawnIt was originally described in 1957 and was the prototypical riminophenazine dye - a bright-red dye that, in its clinical use, results in long-lasting discoloration of the skin and bodily fluids. … [A203144] Although it carries _in vitro_ activity against other mycobacterium, such as _Mycobacterium tuberculosis_, it is generally considered an ineffective treatment in comparison to classic tuberculosis
Products: Fazim 50 mg Capsule, CLOFZIMIN® 100 MG