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Eftrenonacog alfa
go.drugbank.com/drugs/DB11608ApprovedEftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. … Hemophilia B is a blood disorder with an incidence of approximately once every 30,000 male births in all populations and ethnic groups [A31557].
Products: ALPROLIX® 250 UIGestrinone
go.drugbank.com/drugs/DB11619ApprovedGestrinone was developed in the early 1970s and was tested clinically as a weekly oral contraceptive in Europe and North America. … Gestrinone, also known as ethylnorgestrienone, is a synthetic steroid of the 19-nortestosterone group that is marketed in Europe, Australia, and Latin America, though not the United States or Canada, and
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesHuman varicella-zoster immune globulin
go.drugbank.com/drugs/DB11621ApprovedInvestigationalHuman varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). … The therapeutic efficacy is proven if administered within 4 days of exposure to varicella zoster virus.
Synonyms: Human herpesvirus 3 immune globulinDehydrocholic acid
go.drugbank.com/drugs/DB11622ApprovedDehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid [A33022]. It has been used for stimulation of biliary lipid secretion.
Mixtures: PLASIL®ENZIMATICOCandoxatrilat
go.drugbank.com/drugs/DB11623ExperimentalA dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy … A potent inhibitor of neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11), it is used as its 2,3-dihydro-1H-inden-5-yl ester prodrug in the treatment of chronic heart failure.
Perflenapent
go.drugbank.com/drugs/DB11625ApprovedInvestigationalWithdrawnDodecafluoropentane is also known as perfluoropentane or perflenapent.
Categories: Compounds used in a research, industrial, or household settingEptotermin alfa
go.drugbank.com/drugs/DB11631ApprovedWithdrawnA bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis.
Synonyms: BMP-7, OP-1Opicapone
go.drugbank.com/drugs/DB11632ApprovedInvestigationalof these symptoms through the use of a dopamine agonist, a monoamine oxidase B inhibitor (selegiline, rasagiline), a _catechol-O-methyl transferase (COMT)_ inhibitor, or amantadine, or using a modified-release … Opicapone is a potent, reversible, and peripherally-acting third-generation inhibitor of catechol-o-methyltransferase (COMT), an enzyme involved in the breakdown of various catecholamines including dopamine
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InhibitorsDibotermin alfa
go.drugbank.com/drugs/DB11639ApprovedInvestigationalDibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. … BMP-2 is a potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into osteoblasts, thus promoting bone and cartilage formation [A31952].
Synonyms: BMP 2, BMP-2