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Displaying results 1541 - 1550 of 10000 in total
  1. Drug

    Doripenem

    go.drugbank.com/drugs/DB06211
    ApprovedWithdrawn

    Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. … In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that doripenem carried an increased risk of death and lower clinical cure rates

    Products: REDIDOR 500 MG /VIAL, DOREXTRA® DORIPENEM 500 MG
  2. Indication

    Kraurosis Vulvae

    go.drugbank.com/conditions/DBCOND0114418
    Drugs: Conjugated estrogens · Estradiol
    Synonyms: Lichen sclerosus et atrophicus, Lichen sclerosus et atropicus
  3. Drug

    Doxylamine

    go.drugbank.com/drugs/DB00366
    ApprovedInvestigationalVet approved

    It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.

    Mixtures: PRİLAM DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADET, PRİFEMYN DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADETProducts: UNISOM 25 MG TABLET, 20 ADET, Hoggar Night 25 mg Schmelztabletten
  4. Drug

    CHIR-124

    go.drugbank.com/drugs/DB06852
    Experimental

    CHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.

  5. Drug

    Rimonabant

    go.drugbank.com/drugs/DB06155
    ApprovedWithdrawn

    This decision was made after a U.S. advisory panel recommended the medicine not be approved because it may increase suicidal thinking and depression. … It was rejected for approval for use in the United States.

    Products: ACOMPLIA ® COMPRIMIDOS RECUBIERTOS20 MG
  6. Drug

    Etamsylate

    go.drugbank.com/drugs/DB13483
    Investigational

    Products: DICYNONE 500 TABLET 500 mg, DICYNONE INJECTION 250 mg/2 ml
  7. Drug

    Radium Ra 223 dichloride

    go.drugbank.com/drugs/DB08913
    ApprovedInvestigational

    It was first approved by the FDA in May 2013 and is currently marketed under the brand name Xofigo, which was formerly called Alpharadin. … The FDA label includes a warning that Radium Ra 223 Dichloride should not be used in women who are pregnant or may become pregnant due to the high risk of fetal harm.

    Products: XOFIGO 1100 KBQ/ML IV ENJEKSIYON IÇIN ÇÖZELTI IÇEREN FLAKON,1 ADET, Xofigo (Radium-223 Dichloride) 1100 kBq/mL Solution for Injection
  8. Drug

    Axitinib

    go.drugbank.com/drugs/DB06626
    ApprovedInvestigational

    [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. … It is reported to exhibit potency that is 50-450 times higher than that of the first generation VEGFR inhibitors.[L6676] Axitinib is an indazole derivative.

    Synonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamideProducts: INLYTA (TABLETS 1 MG), INLYTA (TABLETS 5 MG)
  9. Drug

    Trametinib

    go.drugbank.com/drugs/DB08911
    ApprovedInvestigational

    [A258298,A258293] It was first approved by the FDA in May 2013 for the treatment of melanoma. … [A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission on June 30, 2014.

    Products: MEKINIST (TABLETS 0.5 MG), MEKINIST (TABLETS 2 MG)
  10. Drug

    Gemifloxacin

    go.drugbank.com/drugs/DB01155
    ApprovedInvestigational

    It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.

    Products: Factive film-coated tablet 320 mg, ONFACT 320 MG FİLM TABLET, 5 ADET