Search

Displaying results 1551 - 1560 of 10000 in total
  1. Drug

    Propranolol

    go.drugbank.com/drugs/DB00571
    ApprovedInvestigational

    Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. … [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]

    Synonyms: 1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol, 1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanolInternational brands: Bedranol SR
  2. Drug

    Anethole trithione

    go.drugbank.com/drugs/DB13853
    Approved

    hepatitis [L2388] and is marketed in certain countries like France, Germany, and China [A32614]. … for many of these aforementioned functions at this time and is only used in limited regions around the world.

  3. Drug

    Protocatechualdehyde

    go.drugbank.com/drugs/DB11268
    Approved

    Also known as protocatechuic aldehyde, protocatechualdehyde is a naturally-occuring phenolic aldehyde that is found in barley, green cavendish bananas, grapevine leaves and root of the herb S. miltiorrhiza … Protocatechualdehyde possesses antiproliferative and pro-apoptotic properties against human breast cancer cells and colorectal cancer cells by reducing the expression of pro-oncogenes β-catenin and cyclin

    Products: O Hui White Extreme Cellight
  4. Drug

    GR270773

    go.drugbank.com/drugs/DB06427
    Investigational

    infusion between healthy adults and those with damaged livers) and NCT00089986 (completed with results, treatment of suspected or confirmed gram-negative severe sepsis in adults, comparing GR270773 with a

  5. Drug

    Eflepedocokin alfa

    go.drugbank.com/drugs/DB16366
    Investigational

    Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant … [A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).[L27666]

    Synonyms: IL-22 DIMER F-652, F-652 (RECOMBINANT FUSION PROTEIN CONSISTING OF TWO HUMAN INTERLEUKIN-22 (IL-22) MOLECULES LINKED TO AN IMMUNOGLOBULIN CONSTANT REGION (IGG2-FC))
  6. Drug

    Formoterol

    go.drugbank.com/drugs/DB00983
    ApprovedInvestigational

    [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers. … [A189528] A major clinical advantage of formoterol over other inhaled beta-agonists is its rapid onset of action (2-3 minutes), which is at least as fast as [salbutamol], combined with a long duration

    Mixtures: DUORESP SP 320/9UG 1X60ED, DUORESP SP 320/9UG 1X60EDCategories: Cytochrome P-450 Substrates, Adrenergic beta-2 Receptor Agonists
  7. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … [A235850,A235855] A Cochrane review of patients being treated for primary hypertension shows that atenolol shows a risk ratio of 0.88 for cardiovascular disease risk and a risk ratio of 0.99 for mortality

    Mixtures: PLENACOR D, PRETENOL C 50 TABLETCategories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor Antagonists
  8. Drug

    Diethyltoluamide

    go.drugbank.com/drugs/DB11282
    Approved

    Diethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. … capable of repelling insects and causing toxicity to humans is still not fully elucidated.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 3-methyl-N,N-diethylbenzamide, N,N-diethyl-m-toluamide
  9. Drug

    Phenylbutazone

    go.drugbank.com/drugs/DB00812
    ApprovedVet approvedWithdrawn

    It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). … A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis.

    Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesSynonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione
  10. Drug

    Aminopterin

    go.drugbank.com/drugs/DB08878
    ApprovedWithdrawn

    In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment of psoriasis. … Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid, 4-amino-4-deoxypteroylglutamate