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Sodium sulfate
go.drugbank.com/drugs/DB09472ApprovedInvestigationalVet approvedSodium ion is the principal cation of the extracellular fluid and plays a large part in the therapy of fluid and electrolyte disturbances. … Sodium Sulfate Anhydrous is the anhydrous, sodium salt form of sulfuric acid. Sodium sulfate anhydrous disassociates in water to provide sodium ions and sulfate ions.
Mixtures: Gavilyte G Tm, GaviLyte - C TMOliceridine
go.drugbank.com/drugs/DB14881ApprovedInvestigational[A218026, A218031, A218036, A218041, A218046] Oliceridine (formerly known as TRV130) is a "biased agonist" at the μ-opioid receptor by preferentially activating the G-protein pathway with minimal receptor … [A218041, A218046] Opioid receptors are seven-transmembrane G-protein-coupled receptors (GPCRs), of which the μ-opioid receptor subtype is predominantly targeted by and is responsible for the effects of
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeFlibanserin
go.drugbank.com/drugs/DB04908ApprovedInvestigationalFlibanserin is the first drug to be approved for hypoactive sexual desire disorder (HSDD) in premenopausal women by the FDA in August 2015. … In December of 2025 the FDA expanded the age of the indication to include postmenopausal women, a first for the FDA and sexual health in that age group. [L54893]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor AgonistsConjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigationalHowever, until 1986 official clinical trials were performed and this product was determined to be effective for the treatment of osteoporosis. … Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.
Categories: Sex Hormones and Modulators of the Genital SystemParamethasone
go.drugbank.com/drugs/DB01384ExperimentalA glucocorticoid with the general properties of corticosteroids. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p737)
Mepenzolate
go.drugbank.com/drugs/DB04843ApprovedWithdrawnIt has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications. … Mepenzolate also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor.
Rifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawnAll of the derivatives have slight different physicochemical properties when compared to the parent structure. … [L4800] This drug was also sent for review to the EMA in 2015 by Dr. Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801]
Diethylpropion
go.drugbank.com/drugs/DB00937ApprovedIllicitInvestigationalIt is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290) … A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeMebanazine
go.drugbank.com/drugs/DB09248ApprovedWithdrawnMebanazine, also known as _Actomol_, is a monoamine oxidase inhibitor (MAOI) belonging to the _hydrazine_ class of chemicals. … It was used in the past as an antidepressant in the 1960s, but has since been discontinued because of its hepatotoxic potential.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSpirapril
go.drugbank.com/drugs/DB01348ApprovedInvestigationalSpirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration.
Categories: Agents Acting on the Renin-Angiotensin System