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Bentiromide
go.drugbank.com/drugs/DB00522ApprovedWithdrawnCases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromide is currently not available in the U.S. or Canada. … Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy.
Categories: Compounds used in a research, industrial, or household settingRifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawn[L4800] This drug was also sent for review to the EMA in 2015 by Dr. Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801] … The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid.
Categories: Drugs for Treatment of Tuberculosis, Heterocyclic Compounds with 4 or More RingsPibrentasvir
go.drugbank.com/drugs/DB13878ApprovedInvestigationalpatients with moderate to severe kidney disease and those who are on dialysis [L940]. … Hepatitis C viral infection often leads to decreased liver function and subsequent liver failure, causing a significantly negative impact on the patients' quality of life.
Categories: Antivirals for treatment of HCV infectionsMiglustat
go.drugbank.com/drugs/DB00419ApprovedInvestigationalHowever, clinical experience with miglustat showed that therapeutic levels of the drug could not be achieved in patients without a high incidence of adverse effect. … It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids.
Synonyms: 1,5-(butylimino)-1,5-dideoxy, D-glucitol, N-(n-Butyl)deoxynojirimycinOxprenolol
go.drugbank.com/drugs/DB01580ApprovedWithdrawnA beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.
Categories: Beta Blocking Agents, Non-Selective, Beta Blocking Agents, Non-Selective, and ThiazidesTrolamine
go.drugbank.com/drugs/DB13747ApprovedInvestigationalTrolamine contains small amounts of diethanolamine and ethanolamine and may also act as an antioxidant against the auto-oxidation of animal and vegetable fats [A27174]. … It is a bifunctional compound that exhibits both properties of alcohols and amines.
Categories: Preparations for Treatment of Wounds and UlcersXanomeline
go.drugbank.com/drugs/DB15357ApprovedInvestigational[L51713] It is approved as part of a combination product alongside [trospium], a muscarinic antagonist that acts primarily on peripheral muscarinic receptors in order to mitigate the risk and severity … of peripheral cholinergic adverse effects.
Procyclidine
go.drugbank.com/drugs/DB00387ApprovedInvestigationalA muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Synonyms: 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol hydrochlorideTrichloroacetate
go.drugbank.com/drugs/DB11152ApprovedInvestigationalTrichloroacetate is also found in cosmetic treatments and topical formulations as a cauterant, which removes condyloma or warts on the skin. … Trichloroacetate, or trichloroacetic acid, is a strong acid prepared by the reaction of chlorine with acetic acid in the presence of a suitable catalyst.
Categories: Compounds used in a research, industrial, or household settingSalsalate
go.drugbank.com/drugs/DB01399ApprovedInvestigationalSalsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. … The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been established.
Categories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticSynonyms: o-Salicylsalicylic acid, O-Salicylcylsalicylsäure