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Displaying results 1561 - 1570 of 10000 in total
  1. Drug

    Meropenem

    go.drugbank.com/drugs/DB00760
    ApprovedInvestigational

    Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. … In August 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of adult patients with complicated urinary tract infections (cUTI).

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
  2. Drug

    Enalaprilat

    go.drugbank.com/drugs/DB09477
    ApprovedInvestigational

    Enalaprilat was originally created to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and left a metallic taste in the mouth. … Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II.

    Categories: Agents Acting on the Renin-Angiotensin SystemProducts: Vasotec IV
  3. Drug

    Idarubicin

    go.drugbank.com/drugs/DB01177
    ApprovedInvestigational

    An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.

    Synonyms: (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside, 4-DemethoxydaunomycinCategories: Topoisomerase II Inhibitors, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index
  4. Drug

    Trimetrexate

    go.drugbank.com/drugs/DB01157
    Approved

    It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against pneumocystis pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect. … A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase.

    Categories: Heterocyclic Compounds, 2-RingProducts: Neutrexin Pws IV 25mg/vial
  5. Drug

    Rifaximin

    go.drugbank.com/drugs/DB01220
    ApprovedInvestigational

    It has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of overt hepatic encephalopathy recurrence; as well as diarrhea-predominant irritable bowel … syndrome (IBS-D) in adult women and men.

    Synonyms: Rifamycin L 105, Rifamycin L 105SVCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  6. Drug

    Calcitriol

    go.drugbank.com/drugs/DB00136
    ApprovedInvestigationalNutraceutical

    Administered orally and intravenously, calcitriol is commonly used as a medication in the treatment of secondary hyperparathyroidism and resultant metabolic bone disease, hypocalcemia in patients undergoing … Calcitriol plays a role in plasma calcium regulation in concert with parathyroid hormone (PTH) by enhancing absorption of dietary calcium and phosphate from the gastrointestinal tract, promoting renal

    Synonyms: 1-alpha-25-Dihydroxyvitamin D3Categories: Vitamin D and Analogues, Cytochrome P-450 Substrates
  7. Drug

    Interferon alfa-n1

    go.drugbank.com/drugs/DB00011
    ApprovedWithdrawn

    Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated.

    Synonyms: Interferon alpha-n1 (INS)Categories: Interferon Type I, Cytochrome P-450 CYP1A2 Inhibitors
  8. Drug

    Insulin pork

    go.drugbank.com/drugs/DB00071
    Approved

    Forms a hexameric structure.

    Categories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersProducts: Regular Purified Pork Insulin Inj
  9. Drug

    Obinutuzumab

    go.drugbank.com/drugs/DB08935
    ApprovedInvestigational

    [L54521] It was developed as a Type II anti-CD20 antibody to improve upon first-generation agents like rituximab. … Obinutuzumab is a humanized anti-CD20 monoclonal antibody designed to treat B-cell malignancies.

    Products: GAZYVA 1000 MG IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET, GAZYVA ® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN 1000 MG / VIAL 40 ML
  10. Indication

    Dry Eyes

    go.drugbank.com/conditions/DBCOND0054254
    Drugs: Acrylic Acid · Carbomer · Carbomer homopolymer type C · Carbopol 974P · Carboxymethylcellulose · Chamomile +12 more
    Synonyms: Vitamin A deficiency with xerophthalmia, Other ocular manifestations of vitamin A deficiency