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Displaying results 1571 - 1580 of 10000 in total
  1. Drug

    Brivudine

    go.drugbank.com/drugs/DB03312
    ApprovedInvestigational

    Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.

  2. Drug

    Prothrombin

    go.drugbank.com/drugs/DB11311
    ApprovedInvestigational

    Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with

    Mixtures: COFACT 250 IU/10 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADET, COFACT 500 IU/20 ML IV ENJEKSIYON IÇIN TOZ IÇEREN FLAKON, 1 ADETSynonyms: Factor II, Factor II (prothrombin)
  3. Drug

    Erdafitinib

    go.drugbank.com/drugs/DB12147
    ApprovedInvestigational

    In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for … [L5956, L5959] Considering urothelial cancer is statistically the fourth most common kind of cancer in the world, the introduction of erdafitinib offers a much-needed new option in the ever-expanding therapeutic

    Categories: Fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitors
  4. Drug

    Abiprubart

    go.drugbank.com/drugs/DB19333
    Investigational

    Abiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395

    Synonyms: Immunoglobulin G4-kappa, anti-[Homo sapiens CD40 (TNFRSF5, tumor necrosis factor receptor (TNFR) superfamily member 5, p50)], humanized monoclonal antibody
  5. Drug

    Chlordiazepoxide

    go.drugbank.com/drugs/DB00475
    ApprovedIllicit

    An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.

    Mixtures: Nu-chlorax Capsules USP
  6. Drug

    Ardeparin

    go.drugbank.com/drugs/DB00407
    ApprovedWithdrawn

    Normiflo was withdrawn from the US market in March 2000. … Ardeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis.

  7. Drug

    Terfenadine

    go.drugbank.com/drugs/DB00342
    ApprovedWithdrawn

    In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.

    Products: TERFENADINA MK 60MG
  8. Drug

    Avatrombopag

    go.drugbank.com/drugs/DB11995
    ApprovedInvestigational

    Avatrombopag (_Doptelet_), is an orally administered, small molecule thrombopoietin receptor (c-Mpl) agonist that increases platelet number without increasing platelet activation,[A33097,L2824] thereby … [L2931] It is administered orally as the salt form avatrombopag maleate.

    Categories: Thrombopoietin Receptor Agonist
  9. Pathway

    Levonorgestrel Action Pathway

    smpdb.ca/view/SMP0125332
    Drug action

    Levonorgestrel (LNG) is a progestin (synthetic progestogen) found in contraceptives (birth control) that are taken orally, in subdermal implants or in intrauterine devices (IUD). Oral contraceptives and IUDs have a low dose, while emerge...

    Drugs: NADH · ATP · Levonorgestrel · Progesterone · Testosterone · Estrone +9 more
    Enzymes: Estradiol 17-beta-dehydrogenase 1, Androgen receptor
  10. Target

    Glycine receptor subunit beta

    go.drugbank.com/bio_entities/BE0000055
    TargetHumans

    Subunit of heteromeric glycine-gated chloride channels (PubMed:11929858, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:23238346, PubMed:25445488, PubMed:34473954, PubMed:8717357). Plays an important role in the down-regulatio...

    Polypeptides: Glycine receptor subunit betaSynonyms: Glycine receptor 58 kDa subunit