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Displaying results 151 - 160 of 359 in total
  1. Pathway

    Aromatic L-Aminoacid Decarboxylase Deficiency

    smpdb.ca/view/SMP0000170
    Disease

    It also results in decreased concentrations of homovanillic acid, S-adenosylmethionine, and 5-hydroxytryptophol in spinal fluid; and epinephrine, norepinephrine in plasma.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Norepinephrine · Epinephrine +4 more
  2. Pathway

    Tyrosine Hydroxylase Deficiency

    smpdb.ca/view/SMP0000497
    Disease

    This enzyme is part of the production of catecholamines such as dopamine, norepinephrine and epinephrine are all essential for normal nervous system function. … Norepinephrine and epinephrine are involved in the autonomic nervous system. Mutations in the TH gene result in reduced activity of the tyrosine hydroxylase enzyme.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Norepinephrine · Epinephrine +4 more
  3. Pathway

    Aromatic L-Aminoacid Decarboxylase Deficiency

    smpdb.ca/view/SMP0125610
    Disease

    It also results in decreased concentrations of homovanillic acid, S-adenosylmethionine, and 5-hydroxytryptophol in spinal fluid; and epinephrine, norepinephrine in plasma.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Norepinephrine · Epinephrine +4 more
  4. Drug

    Fenproporex

    go.drugbank.com/drugs/DB01550
    ApprovedIllicitWithdrawn

    Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. It is listed as an illicit substance in many countries due to addiction issues and liste...

  5. Drug

    Moxisylyte

    go.drugbank.com/drugs/DB09205
    Approved

    Moxisylyte, denominated as thymoxamine in the UK, is a specific and orally active α1-adrenergic antagonist. According to the WHO, moxisylyte is approved since 1987 and in the same year, it acquired the denomination of orphan product by t...

  6. Drug

    Reserpine

    go.drugbank.com/drugs/DB00206
    ApprovedWithdrawn

    Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals.

  7. Pathway

    Tyrosine Hydroxylase Deficiency

    smpdb.ca/view/SMP0125611
    Disease

    This enzyme is part of the production of catecholamines such as dopamine, norepinephrine and epinephrine are all essential for normal nervous system function. … Norepinephrine and epinephrine are involved in the autonomic nervous system. Mutations in the TH gene result in reduced activity of the tyrosine hydroxylase enzyme.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Norepinephrine · Epinephrine +4 more
  8. Drug

    Zimelidine

    go.drugbank.com/drugs/DB04832
    ApprovedWithdrawn

    Zimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving many organs including skin exa...

  9. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    TCAs are potent inhibitors of serotonin and norepinephrine reuptake.

    Categories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Tricyclics and Other Norepinephrine-reuptake Inhibitors
  10. Drug

    Prazosin

    go.drugbank.com/drugs/DB00457
    ApprovedInvestigational

    Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefit...