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Ropinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalIn 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.
Products: REQUIP IRMood Disorders
go.drugbank.com/conditions/DBCOND0027889Synonyms: Disturbance in affect, NOS, Disturbance in affect (finding)Etofenamate
go.drugbank.com/drugs/DB08984InvestigationalEtofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).
Categories: Antiinflammatory Preparations, Non-Steroids for Topical Use, Topical Products for Joint and Muscular PainProducts: RHEUMON DEPOT IM 1 AMPUL, ETOFAST 1 G/2 ML IM ENJEKSİYONLUK ÇÖZELTI, 3 ADETRecurrent Miscarriages
go.drugbank.com/conditions/DBCOND0032265Drugs: DydrogesteroneSynonyms: Investigation or care in a nonpregnant woman with history of recurrent pregnancy lossGelatin
go.drugbank.com/drugs/DB11242ApprovedInvestigationalVet approvedWithdrawnAn increasing number of novel applications have been found for collagen and gelatin.[A32426] Gelatin is generally recognized as safe (GRAS) by the FDA to be a non-hazardous food or food ingredient. … [A32432] Interestingly, horse gelatin has been studied and it was found that in the horse, gelatin influences the homeostasis of the amino acids required for cartilage synthesis [A32434].
Mixtures: Gelaspan Solution for infusion, GELOFUSINE IN 500ML PLASTIC CONTAINERGTP-binding protein Rheb
go.drugbank.com/bio_entities/BE0004594TargetHumansRHEB is also required for localization of the TSC-TBC complex to lysosomal membranes (PubMed:24529379). … In response to starvation, RHEB is inactivated by the TSC-TBC complex, preventing activation of mTORC1 (PubMed:24529379, PubMed:33157014). Has low intrinsic GTPase activity (PubMed:15340059)
Synonyms: Ras homolog enriched in brainAfamelanotide
go.drugbank.com/drugs/DB04931Approved[L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125] … [L9086] It differs structurally from its endogenous counterpart by only two amino acids - these structural differences improve biological efficacy by imparting a greater affinity for its target and a longer
Categories: Protectives Against UV-Radiation for Systemic Use, Compounds used in a research, industrial, or household settingSynonyms: MT-I, Melanotan IZinc monoethylfumarate
go.drugbank.com/drugs/DB15818ExperimentalSynonyms: Monoethyl fumarate zinc salt