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Vonicog alfa
go.drugbank.com/drugs/DB12872ApprovedInvestigational[A264389] Vonicog alfa works to reduce bleeding events and bleeding times in patients with vWD, who have deficiencies in VWF.[A264389] … [A264444] Used to treat von Willebrand Disease (vWD), it mimics the biological actions of endogenous VWF,[L51274] which is a critical plasma glycoprotein involved in platelet adhesion and aggregation.
Pizotifen
go.drugbank.com/drugs/DB06153ApprovedPizotifen belongs to the class of antamines and is related to [cyproheptadine].[A32532] It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. … It exhibits weak anticholinergic, antihistamine, and antikinin actions in addition to sedative and appetite-stimulating properties [L2292].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeGatralimab
go.drugbank.com/drugs/DB16528Investigationaland Repeat Treatment). … Gatralimab is under investigation in clinical trial NCT02389452 (Study of Safety and Efficacy of 6 Ml Synvisc-one (Hylan G-F 20) in Indian Patients With Symptomatic Osteoarthritis of Knee(s) After Initial
Cinnamyl alcohol
go.drugbank.com/drugs/DB14186ApprovedCinnamyl alcohol has been shown to be a skin sensitizer, with a NOEL (No Effect Level) of ~4% [A34266]. Sensitivity to cinnamyl alcohol may be identified with a clinical patch test. … Due to the low levels found in cinnamon, cinnamyl alcohol is usually supplied as [DB14184] within commercial products.
Benzphetamine
go.drugbank.com/drugs/DB00865ApprovedIllicitA sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeOrlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIn some individuals, diet and exercise are insufficient to maintain weight loss, and pharmacological or surgical intervention is required. … Obesity-related complications lead to significant personal and economic burden by reducing quality of life and increasing the cost of healthcare.
Phloxine B
go.drugbank.com/drugs/DB13911ApprovedWithdrawnPhloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing … These tablets allow patients to visualise areas where more brushing and flossing are needed.
Synonyms: D&C Red No. 28Minocycline
go.drugbank.com/drugs/DB01017ApprovedInvestigational[A190723] Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines.
Products: PERIOCLINE PERIODONTAL OINTMENT 2% W/WPergolide
go.drugbank.com/drugs/DB01186ApprovedVet approvedWithdrawnPergolide is a long-acting dopamine agonist approved in 1982 for the treatment of Parkinson’s Disease. It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors...
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: PERGOLIDE MYLAN GENERICSDinoprostone
go.drugbank.com/drugs/DB00917ApprovedInvestigationalAs a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour. … It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts.