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VLA-4 (very late antigen-4)
go.drugbank.com/bio_entities/BE0010014TargetHumansIntegrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. … Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1.
Synonyms: Fibronectin receptor subunit betaNACHT, LRR and PYD domains-containing protein 3
go.drugbank.com/bio_entities/BE0010347TargetHumansSensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis (PubMed:16407889, PubMed:1840367...
Synonyms: Angiotensin/vasopressin receptor AII/AVP-likeKinesin-like protein KIF11
go.drugbank.com/bio_entities/BE0001852TargetHumansMotor protein required for establishing a bipolar spindle and thus contributing to chromosome congression during mitosis (PubMed:19001501, PubMed:37728657). Required in non-mitotic cells for transport of secretory proteins from the Golgi...
Synonyms: Thyroid receptor-interacting protein 5Enprofylline
go.drugbank.com/drugs/DB00824ApprovedWithdrawnEnprofylline is a derivative of theophylline which shares bronchodilator properties. Enprofylline is used in asthma, chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and ...
Categories: Purinergic P1 Receptor Antagonists, Adenosine A2 Receptor AntagonistsEucalyptus oil
go.drugbank.com/drugs/DB11114ApprovedEucalyptus oil is a distilled oil derived from the leaves of the tree Eucalyptus. It is shown to be effective in reducing pain, swelling, and inflammation via its modulatory effect on the immune response. It is also shown to exhibit anti...
Mixtures: Vaporizing Chest Rub 4 oz. 3 pkRegadenoson
go.drugbank.com/drugs/DB06213ApprovedInvestigationalRegadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
Categories: Purinergic P1 Receptor Agonists, Adenosine A receptor agonistsMiconazole
go.drugbank.com/drugs/DB01110ApprovedInvestigationalVet approvedMiconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole i...
Mixtures: KRIM PI KANG SHUANGCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2A6 InhibitorsL-selectin
go.drugbank.com/bio_entities/BE0010361TargetHumansCalcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28011641, PubMed:28489325). Mediates the adherence of lymphocytes to endothelial cells of high endothelial ven...
Synonyms: Lymph node homing receptorCalcium-activated potassium channel subunit beta-4
go.drugbank.com/bio_entities/BE0004424TargetHumansRegulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium se...
Synonyms: Charybdotoxin receptor subunit beta-4Calcium-activated potassium channel subunit beta-2
go.drugbank.com/bio_entities/BE0003196TargetHumansRegulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers ra...
Synonyms: Charybdotoxin receptor subunit beta-2