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Tazobactam
go.drugbank.com/drugs/DB01606ApprovedInvestigationalPiperacillin-tazobactam was initially approved by the FDA in 1994, and ceftolozane-tazobactam was approved by the FDA in 2014[FDA label], providing wider antibacterial coverage for gram-negative infections … It is combined with [Piperacillin] and [Ceftolozane] for the treatment of a variety of bacterial infections.
Mixtures: PIPERACILINA 4000 MG Y TAZOBACTAM 500 MG, TAZOJECT 4 G/ 0,5G IV ENJEKSIYONLUK LIYOFILIZE TOZ, 25 ADETCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingXylitol
go.drugbank.com/drugs/DB11195ApprovedInvestigationalThe recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events [A22081]. … Xylitol is a non-fermentable sugar alcohol by most plaque bacteria, indicating that it cannot be fermented into cariogenic acid end-products [A32423].
Synonyms: D-XylitolMixtures: Fluor-a-day, Fluor-a-dayFotemustine
go.drugbank.com/drugs/DB04106InvestigationalSynonyms: (+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate, Diethyl-1-(3-(2-chloroethyl)-3-nitrosoureido)ethylphosphonateProducts: Muphoran 200 mg/4ml Pulver und Lösungsmittel zur Herstellung einer Infusionslösung, MUPHORAN 208 MG FLAKON, 1 ADETTolperisone
go.drugbank.com/drugs/DB06264InvestigationalIt possesses a high affinity for nervous system tissue, reaching highest concentrations in brain stem, spinal cord and peripheral nerves.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: TOLPERISON-NEURAX 50 MG, Netolp 50 mg Film Kaplı Tablet, 30 ADETPranlukast
go.drugbank.com/drugs/DB01411InvestigationalPranlukast is a cysteinyl leukotriene receptor-1 antagonist. … It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsProducts: PRANLUX 50 MG SAŞE, 30 SAŞE, PRANLUX 50 MG SAŞE, 90 SAŞEDoconexent
go.drugbank.com/drugs/DB03756ApprovedInvestigationalA mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. … It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin, and retina thus plays an important role in their development and function.
Mixtures: SIMILAC ALIMENTUM 400 G TOZ, Herbs of Gold Salmon Oil 1000 mgCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 InhibitorsYohimbine
go.drugbank.com/drugs/DB01392ApprovedInvestigationalVet approvedWithdrawnA plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Categories: Cytochrome P-450 Substrates, Genito Urinary System and Sex HormonesInternational brands: Baron-XTransitional endoplasmic reticulum ATPase
go.drugbank.com/bio_entities/BE0004572TargetHumansThe transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic
Synonyms: 15S Mg(2+)-ATPase p97 subunitCalcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt is a salt that is solid at room temperature, and it behaves as a typical ionic halide. … It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers.
Synonyms: calcium(2+) chlorideInternational brands: LiquiCal-D 400Papain
go.drugbank.com/drugs/DB11193ApprovedWithdrawnPapain, also known as papaya proteinase I, is a cysteine protease (EC 3.4.22.2) enzyme that is found in species of papaya, _Carica papaya_ and _Vasconcellea cundinamarcensis_. … Present in over-the-counter mixture products consisting of different digestive enzymes, its active site contains a catalytic diad that plays a role in breaking peptide bonds.
Mixtures: NATURE'S BOUNTY NATUREL B-COMPLEX AND B-12 TABLET, 90 ADET, BIOGROW® VITEProducts: Papaya Enzyme - Tablet 30 mg, NORIPAPAIN 150 000 USP UNITS TABLET