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Displaying results 1681 - 1690 of 10000 in total
  1. Drug

    Scorpion (centruroides) immune Fab2 antivenin (equine)

    go.drugbank.com/drugs/DB13905
    Approved

    Envenomation by a scorpion sting can result in serious cardiovascular effects [A32483]. … This drug is a polyvalent antivenin proven to be useful against scorpion stings.

    Synonyms: Centruroides (scorpion) Immune F(ab')2 (equine), Centruroides (scorpion) immune F(ab')2 (equine) injectionProducts: ALVENO AC 10 ML IV ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET FLAKON+1 ADET ÇÖZÜCÜ AMPUL, ACSERA 5 ML ENJEKSIYONLUK COZELTI KONSANTRESI ICEREN FLAKON
  2. Pathway

    Simvastatin Action Pathway

    smpdb.ca/view/SMP0000082
    Drug action

    Cytochrome P450 (CYP) enzymes, CYP3A4, CYP3A5, and CYP2C8, have been implicated in this activation step; CYP3A4/5 are responsible for ≥ 80% of simvastatin metabolism while CYP2C8 (not shown in pathway) … The simvastatin hydroxy acid inhibits cholesterol synthesis via the mevalonate pathway by competitively inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase.

    Drugs: Cholecalciferol · ATP · Simvastatin · Magnesium cation · Iron · Dimethylallyl Diphosphate +9 more
    Enzymes: 3-Hydroxy-3-methylglutaryl-coenzyme A reductase
  3. Indication

    Puberty, Delayed

    go.drugbank.com/conditions/DBCOND0001010
    Drugs: Fluoxymesterone · Methyltestosterone · Testosterone · Testosterone propionate
    Synonyms: Delay in sexual development AND/OR puberty (finding), Delay in sexual development and puberty, NEC -RETIRED-
  4. Drug

    Thyrotropin alfa

    go.drugbank.com/drugs/DB00024
    ApprovedInvestigationalVet approved

    Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. … It is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues

    Products: THYROGEN 0,9 MG/1,08 ML IM ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 2 FLAKON, THYROGEN®
  5. Indication

    Breast Pain

    go.drugbank.com/conditions/DBCOND0033589
    Drugs: Vitex agnus-castus fruit extract
    Synonyms: Pain in breast, Pain in the breast
  6. Drug

    Colistin

    go.drugbank.com/drugs/DB00803
    ApprovedInvestigational

    It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. … Colistin is less toxic than Polymyxin B, but otherwise similar; the methanesulfonate is used orally.

    Mixtures: Coly-Mycin S, Coly-Mycin SCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  7. Drug

    2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER

    go.drugbank.com/drugs/DB08643
    Experimental

    Synonyms: 2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER
  8. Drug

    Conestat alfa

    go.drugbank.com/drugs/DB09228
    Approved

    C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. … Marketed as the product Ruconest (FDA), this drug is indicated for the treatment of acute attacks of hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency in adults.

    Categories: Drugs Used in Hereditary AngioedemaSynonyms: Recombinant human C1-INH
  9. Drug

    Diltiazem

    go.drugbank.com/drugs/DB00343
    ApprovedInvestigational

    Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. … [T28] Being a potent vasodilator, diltiazem is used clinically as an antihypertensive, anti-arrhythmic, and as an anti-anginal agent [L6289] for the management of cardiovascular conditions such as hypertension

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester, (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate
  10. Drug

    BCG vaccine

    go.drugbank.com/drugs/DB12768
    ApprovedInvestigationalWithdrawn

    BCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.

    Products: SII-BCG 1 ML ID ENJEKSIYONLUK SUSPANSIYON ICIN LIYOFILIZE TOZ ICEREN COK DOZLU FLAKON, 1 ADET, SII-BCG 1 ML ID ENJEKSIYONLUK SUSPANSIYON ICIN LIYOFILIZE TOZ ICEREN COK DOZLU FLAKON, 10 ADET