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Trioxsalen
go.drugbank.com/drugs/DB04571ApprovedWithdrawnLike other psoralens it causes photosensitization of the skin. … cross-linked specifically to a mutant mRNA sequence without affecting normal transcripts differing at even a single base pair.
Tislelizumab
go.drugbank.com/drugs/DB14922ApprovedInvestigational[L50346] It has subsequently been approved for additional cancers in the US and EU. [L49349] … It was engineered to have a nullified Fc portion, thus minimizing binding to FcγR on macrophages and limiting treatment resistance via antibody-dependent phagocytosis.
Limaprost
go.drugbank.com/drugs/DB09211InvestigationalLimaprost (as Limaprost alfadex; CAS number 88852-12-4) is an oral prostaglandin E1 analog. … It also improves poor blood flow in the nerve tissue in cervical spondylosis and normalizes nerve function.
Categories: Prostaglandins ECod liver oil
go.drugbank.com/drugs/DB11321ApprovedNutraceuticalVet approvedIt is used as an adjunct treatment and preventative therapy of rickets, osteomalacia and osteoporosis while meeting the consumption criteria.
Vonicog alfa
go.drugbank.com/drugs/DB12872ApprovedInvestigational[A264444] Used to treat von Willebrand Disease (vWD), it mimics the biological actions of endogenous VWF,[L51274] which is a critical plasma glycoprotein involved in platelet adhesion and aggregation.
Synonyms: (618-THREONINE,709-ASPARTIC ACID)VON WILLEBRAND FACTOR HOMO SAPIENS (1381A>T,1472H>D VARIANT) BLOOD COAGULATION FACTORGadobenic acid
go.drugbank.com/drugs/DB00743ApprovedInvestigational[A263086] It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity. … [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the biliary system, it is a useful contrast agent for liver MRI.
Aclidinium
go.drugbank.com/drugs/DB08897ApprovedIt has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Fluorodopa (18F)
go.drugbank.com/drugs/DB13848ApprovedInvestigationalFluorodopa F 18 is a fluorinated analog of [levodopa] used as a diagnostic agent for positron emission tomography (PET) in the evaluation of Parkinsonian syndromes. … [L12849] Fluorodopa F 18 PET is used adjunctly with other diagnostic investigations and serves primarily to visualize dopaminergic nerve terminals in the striatum.[L12849]
Dioxybenzone
go.drugbank.com/drugs/DB11221ApprovedWithdrawnIt absorbed UV-B and UV-AII rays. Dioxybenzone is an approved sunscreen ingredient in concentrations up to 3% [L2525].
Ulipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalevidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily debated due to ethical concerns related to abortion (Rosato et … It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor.
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