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Gabapentin Action Pathway
smpdb.ca/view/SMP0124712Drug actionThe role of gabapentin is to bind to the α2δ-1 subunit of voltage-gated calcium channels, thereby inhibiting the voltage gated calcium channels. … When an action potential arrives at the nerve terminal, calcium channels are activated allowing influx of calcium ions, which stimulates the release of neurotransmitters by causing the exocytotic vesicle
Enzymes: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent N-type calcium channel subunit alpha-1BDexbrompheniramine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175073Drug actionFurthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1Cyproheptadine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175075Drug actionFurthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1Promethazine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175084Drug actionFurthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1Chloropyramine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175097Drug actionFurthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1Acrivastine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175099Drug actionFurthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1Ebastine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175100Drug actionFurthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1Quetiapine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175112Drug actionFurthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1Isothipendyl H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175114Drug actionFurthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1Deptropine H1-Antihistamine Immune Response Action Pathway
smpdb.ca/view/SMP0175120Drug actionFurthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.
Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1