Search
Phenobarbital Action Pathway
smpdb.ca/view/SMP0126831Drug actionFunctioning as a nonselective depressant of the central nervous system, it engages inhibitory gamma-aminobutyric acid subtype receptors, thereby modulating chloride currents across receptor channels and … Phenobarbital is absorbed to varying degrees through oral, rectal, or parenteral routes, with the salts exhibiting quicker absorption compared to the acids.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Phenobarbital · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Zopiclone Action Pathway
smpdb.ca/view/SMP0126832Drug actionOperating outside the benzodiazepine and barbiturate realms, it interacts with the gamma-aminobutyric acid-benzodiazepine (GABABZ) receptor complex, demonstrating both benzodiazepine-like and some barbiturate-like
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2GABA
smpdb.ca/view/SMP0127038PhysiologicalGamma-aminobutyric acid (GABA) is an amino acid that serves as the primary inhibitory neurotransmitter in the brain and a major inhibitory neurotransmitter in the spinal cord. … After synthesis, it is loaded into synaptic vesicles by the vesicular inhibitory amino acid transporter. SNARE complexes help dock the vesicles into the plasma membrane of the cell.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Ubidecarenone
go.drugbank.com/drugs/DB09270ApprovedInvestigationalNutraceuticalUbidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid...
Mixtures: Folic-K, Folica-VLorazepam Action Pathway
smpdb.ca/view/SMP0125053Drug actionLorazepam is a short-acting benzodiazepine commonly used for the short-term relief of anxiety symptoms related to anxiety disorders and anxiety associated with depressive symptoms such as anxiety-associated insomnia. It is as well used a...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Clonazepam Action Pathway
smpdb.ca/view/SMP0125054Drug actionClonazepam is a long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures. Clonazepam ballosterically binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand-...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Midazolam Action Pathway
smpdb.ca/view/SMP0125055Drug actionMidazolam is a short-acting injectable benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders. Midazolam allosterically binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Bromazepam Action Pathway
smpdb.ca/view/SMP0125070Drug actionBromazepam is a short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. Bromazepam is a lipophilic, long-acting benzodiazepine and with sedative, hypnotic, anxiolytic and skeletal mu...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Zolpidem Action Pathway (New)
smpdb.ca/view/SMP0125072Drug actionZolpidem is a sedative hypnotic used for the short-term treatment of insomnia to improve sleep latency. Zolpidem binds on the benzodiazepine receptors in the post-synaptic GABA-A ligand-gated chloride channel in different sites of the ce...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Chlordiazepoxide Action Pathway
smpdb.ca/view/SMP0126120Drug actionChlordiazepoxide is a benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period. Chlordiazepoxide binds to stereospecific benzodiazepine (BZD) b...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Chlordiazepoxide · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2