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Colchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961. … [L8192] Colchicine is used in the treatment of gout flares and Familial Mediterranean fever,[L8138] and prevention of major cardiovascular events.
Categories: P-glycoprotein inducers, P-glycoprotein substratesProducts: L-CISIN, Colctab 1 mg TablettenDigitoxin
go.drugbank.com/drugs/DB01396ApprovedWithdrawnA cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSalsalate
go.drugbank.com/drugs/DB01399ApprovedInvestigationalSalsalate is a nonsteroidal anti-inflammatory agent for oral administration. … A significant portion of the parent compound is absorbed unchanged and undergoes rapid esterase hydrolysis in the body. The parent compound has an elimination half-life of about 1 hour.
Categories: Non COX-2 selective NSAIDSSynonyms: 2-Carboxyphenyl salicylate, o-Salicylsalicylic acidMethotrimeprazine
go.drugbank.com/drugs/DB01403ApprovedA phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AntagonistsSynonyms: (-)-(2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine, (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazineCiclesonide
go.drugbank.com/drugs/DB01410ApprovedInvestigationalCiclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco.
Mixtures: LUXNID 2/200 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL,120 KAPSÜL, LUXNID 2/200 MCG INHALASYON IÇIN TOZ IÇIEREN KAPSÜL,60 KAPSÜLCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTheobromine
go.drugbank.com/drugs/DB01412InvestigationalTheobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. … It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingCefacetrile
go.drugbank.com/drugs/DB01414InvestigationalVet approvedA derivative of 7-aminocephalosporanic acid.
Categories: Heterocyclic Compounds, 2-RingProducts: CELOR ENTRAVENÖZ AMPUL 2G, 1 ADET, CELOR ENTRAVENÖZ AMPUL 2G, 5 ADETCefpodoxime
go.drugbank.com/drugs/DB01416ApprovedInvestigationalVet approvedCommonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime. … Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria.
Mixtures: INFEX PLUS 100/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML, INFEX PLUS 40/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 MLCategories: Heterocyclic Compounds, 2-RingAntrafenine
go.drugbank.com/drugs/DB01419ApprovedAntrafenine is a piperazine derivative drug that acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen. … It is not widely used as it has largely been replaced by newer drugs.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingTestosterone propionate
go.drugbank.com/drugs/DB01420ApprovedInvestigationalVet approvedWithdrawnTestosterone propionate is a slower-releasing anabolic steroid with a short half-life. … It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates