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Displaying results 1741 - 1750 of 6951 in total

Drug
Phenindamine
go.drugbank.com/drugs/DB01619
Approved
Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. … The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury
Categories: Antihistamines for Systemic Use
Drug
Ajmaline
go.drugbank.com/drugs/DB01426
ApprovedWithdrawn
In these cases, abnormal prolongation of the HV interval has been taken as a proof for infrahisian conduction defects tributary for permanent pacemaker implantation. … It has also been used for many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and syncope.
Drug
Azelastine
go.drugbank.com/drugs/DB00972
ApprovedInvestigational
Azelastine, a phthalazine derivative, is an antihistamine available as an intranasal spray for the treatment of allergic and vasomotor rhinitis and as an ophthalmic solution for the treatment of allergic … [L8240,L8270] Azelastine is also available in combination with fluticasone propionate as a nasal spray marketed under the trade name Dymista™, which is indicated for the symptomatic treatment of seasonal
Categories: Antihistamines for Systemic Use
Drug
Captopril
go.drugbank.com/drugs/DB01197
ApprovedInvestigational
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Categories: Antihypertensive Agents Indicated for Hypertension
Drug
Naftifine
go.drugbank.com/drugs/DB00735
Approved
Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum
Categories: Antifungals for Topical Use, Antifungals for Dermatological Use
Drug
Proline
go.drugbank.com/drugs/DB00172
ApprovedInvestigationalNutraceutical
It is an essential component of collagen and is important for proper functioning of joints and tendons.
Mixtures: GLAMIN SOLUTION FOR INFUSION, KABIVEN EMULSION FOR INFUSION
Drug
Esmolol
go.drugbank.com/drugs/DB00187
ApprovedInvestigationalWithdrawn
Other esmolol formulations are still available for use.[L43942] … The FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride that supply 250 milligrams/milliliter of concentrated esmolol per 10-milliliter ampule
Categories: Antihypertensive Agents Indicated for Hypertension, Adrenergic beta-1 Receptor Antagonists
Drug
Quinine
go.drugbank.com/drugs/DB00468
ApprovedInvestigational
Quinine (GLS-1200) was also investigated in clinical trials for its efficacy in preventing SARS-CoV-2 infection (NCT04408183, terminated) and is planned to be evaluated for preventing sinusitis after endoscopic … It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
Drug
Neisseria meningitidis serogroup B recombinant LP2086 B01 protein variant antigen
go.drugbank.com/drugs/DB10285
ApprovedInvestigational
Neisseria meningitidis serogroup b recombinant lp2086 b01 protein variant antigen is a sterile vaccine for intramuscular injection indicated for the active immunization to prevent invasive disease caused
Mixtures: TRUMENBA SUSPENSION FOR INJECTION IN SINGLE-DOSE PRE-FILLED SYRINGE 0.5ML
Drug
Rusfertide
go.drugbank.com/drugs/DB17724
ApprovedInvestigational
[L64113] It is the first hepcidin mimetic approved for polycythemia vera.[L64113] … [L64098] The FDA approved rusfertide on August 28, 2026 for the treatment of erythrocytosis in adults with polycythemia vera, a blood cancer.