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Polyneuropathies
go.drugbank.com/conditions/DBCOND0030109Drugs: VutrisiranSynonyms: Other neurologic disorders in Lyme diseaseElevation of serum triglyceride levels
go.drugbank.com/conditions/DBCOND0097366Synonyms: Increases in triglycerides, Increase in blood triglyceridesMethyldopa
go.drugbank.com/drugs/DB00968ApprovedInvestigational[A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. … [A232224] First introduced in 1960 as an antihypertensive agent, methyldopa was considered to be useful in certain patient populations, such as pregnant women and patients with renal insufficiency.
Categories: Adrenergic alpha-2 Receptor Agonists, Central alpha-2 Adrenergic AgonistSynonyms: α-methyl-L-dopa, 3-Hydroxy-alpha-methyl-L-tyrosineInterferon-inducible protein AIM2
go.drugbank.com/bio_entities/BE0011287TargetHumansInflammasomes are supramolecular complexes that assemble in the cytosol in response to pathogens and other damage-associated signals and play critical roles in innate immunity and inflammation (PubMed: … Also acts as a regulator of neurodevelopment via its role in the DNA damage response: acts by promoting neural cell death in response to DNA damage in the developing brain, thereby purging genetically
Synonyms: Absent in melanoma 2Ambrisentan
go.drugbank.com/drugs/DB06403ApprovedInvestigationalPatients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. … In addition, it is approved in the United States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and to improve exercise ability.
Synonyms: (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acidCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesHydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedHydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. … Hydrogen peroxide is formed in the body of mammals during reduction of oxygen either directly in a two-electron transfer reaction [L2024].
Mixtures: BANEN Rinse-free Hand Sanitizer (II), Dio WhiteningCategories: Compounds used in a research, industrial, or household settingVomit
go.drugbank.com/conditions/DBCOND0052584Synonyms: (Vomiting (& [C/O] or [symptoms])) or (rumination)Tizanidine
go.drugbank.com/drugs/DB00697ApprovedInvestigationalInitially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons … Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574].
Synonyms: 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazoleMixtures: ALGI - B® TABLETAS, ALGI - B® TABLETASPrazosin
go.drugbank.com/drugs/DB00457ApprovedInvestigationalPrazosin is a drug used to treat hypertension. Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988. … [L5828] It belongs to the class of drugs known as alpha-1 antagonists.
Synonyms: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine, 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolineCategories: P-glycoprotein inhibitors, P-glycoprotein substratesTriethylenetetramine
go.drugbank.com/drugs/DB06824ApprovedInvestigationalTriethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, [spermidine] and [spermine]. … [A19333] Initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease,[A19334] TETA is currently indicated to treat adults with stable Wilson’s disease who are de-coppered and
Categories: Compounds used in a research, industrial, or household setting