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Displaying results 1751 - 1760 of 10000 in total
  1. Drug

    Desipramine

    go.drugbank.com/drugs/DB01151
    Approved

    They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, desipramine does not affect mood or arousal, but may cause sedation. … The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission.

    Synonyms: N-(3-methylaminopropyl)iminobibenzylProducts: DESIPRAM 25 MG TABLET, 100 ADET, Desipramine-10 - Tab 10mg
  2. Drug

    Thallous chloride

    go.drugbank.com/drugs/DB09316
    ApprovedWithdrawn

    Thallous chloride (also known as Thallium(I) chloride) is a colourless solid intermediate in the isolation of thallium from its ores. … This solid crystallizes in the caesium chloride motif. It is used as a diagnostic radiopharmaceutical. It is used for diagnosis of heart and parathyroid problems.

    Products: THALLOUS CHLORIDE (Tl201) INJECTION 37 MBq/ml, TAEK-PHT 201-TlCl (TALYUM KLORÜR) 37 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET
  3. Pathway

    Pyruvate Dehydrogenase Complex Deficiency

    smpdb.ca/view/SMP0125772
    Disease

    PDHA1 encodes the pyruvate dehydrogenase complex (PDC) a critical complex that converts pyruvate from glycolysis to acetyl CoA for the citric acid cycle. … Pyruvate dehydrogenase complex deficiency results from a mutation in the E1-alpha polypeptide gene (PDHA1).

    Drugs: Pyruvic acid · Biotin · Adenosine phosphate · Glutathione · NADH · ATP +13 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
  4. Drug

    Choline alfoscerate

    go.drugbank.com/drugs/DB04660
    Investigational

    (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem] … A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids.

    Synonyms: sn-3-GPC, sn-Glycero-3-phosphocholineProducts: MEDOTİLİN 1000 MG/ 4 ML IM/IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPÜL, 3 ADET
  5. Drug

    Petrolatum

    go.drugbank.com/drugs/DB11058
    ApprovedInvestigational

    It is used as an ointment base, topical protectant, and lubricant.

    Mixtures: Veradex-E, Ma Ying Long Musk HemorrhoidsCategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Siponimod

    go.drugbank.com/drugs/DB12371
    ApprovedInvestigational

    It was approved by the FDA on March 26, 2019 [L5792] and by Health Canada on February 20, 2020. … [L5801] MS is one of the most common causes of neurological disability in young adults and is found to occur more frequently in women than in men.[A176474,L5792]

    Products: MAYZENT FILM-COATED TABLET 2MG
  7. Drug

    Vasopressin

    go.drugbank.com/drugs/DB00067
    ApprovedInvestigational

    [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. … [A228008, A228013, A228018, L31413] The vasopressive effect of posterior pituitary gland extracts was noted in 1895, while vasopressin itself was not purified until 1951.

    Products: Vasopressin in 0.9% Sodium Chloride, VASOPRESINA 20 UI/ML
  8. Drug

    Ramosetron

    go.drugbank.com/drugs/DB09290
    Investigational

    Currently, ramosetron is only approved for use Japan and in certain Southeast Asian countries. … Ramosetron is a _serotonin 5-HT3 receptor antagonist_ commonly employed to treat nausea and vomiting, in addition to certain diarrheal conditions.

    Products: NASEA(R) TABLET 0.1 MG, IRRIBOW TABLET 5 MCG
  9. Drug

    Aclidinium

    go.drugbank.com/drugs/DB08897
    Approved

    FDA approved on July 24, 2012. … Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD).

    Mixtures: Duaklir Genuair 340/12 mcg Inhalation PowderProducts: EKLIRA®GENUAIR® 322 MCG/DOSIS, Eklira Genuair 322 mcg Inhalation Powder
  10. Drug

    Fluocinolone acetonide

    go.drugbank.com/drugs/DB00591
    ApprovedInvestigationalVet approved

    [T357] It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices. … [T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676]

    Mixtures: InfectoCiproCort 3 mg/ml + 0,25 mg/ml Ohrentropfen, Lösung, OCIDERM-NProducts: FLUNOLONE-V CREAM 0.25 mg/g