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Lopinavir
go.drugbank.com/drugs/DB01601ApprovedInvestigationalLopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, fi...
Mixtures: LOPINAVIR E RITONAVIR MYLAN, LOPINAVIR E RITONAVIR MYLANRitonavir
go.drugbank.com/drugs/DB00503ApprovedInvestigationalRitonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimen...
International brands: BusvirMixtures: LOPINAVIR E RITONAVIR MYLAN, LOPINAVIR E RITONAVIR MYLANProteasome subunit beta type-10
go.drugbank.com/bio_entities/BE0004738TargetHumansThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic
Synonyms: Multicatalytic endopeptidase complex subunit MECl-1Splicing factor, proline- and glutamine-rich
go.drugbank.com/bio_entities/BE0008965TargetHumansPlays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune … The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity.
Synonyms: DNA-binding p52/p100 complex, 100 kDa subunitInter-alpha-trypsin inhibitor heavy chain H2
go.drugbank.com/bio_entities/BE0009060TargetHumansMay act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are ...
Synonyms: Inter-alpha-trypsin inhibitor complex component IIInter-alpha-trypsin inhibitor heavy chain H1
go.drugbank.com/bio_entities/BE0009080TargetEnzymeHumansMay act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are ...
Synonyms: Inter-alpha-trypsin inhibitor complex component IIIDoxercalciferol
go.drugbank.com/drugs/DB06410ApprovedInvestigationalDoxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated f...
Categories: Sex Hormones and InsulinsMafenide
go.drugbank.com/drugs/DB06795ApprovedVet approvedWithdrawnMafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the F...
Categories: Genito Urinary System and Sex HormonesTetracosactide
go.drugbank.com/drugs/DB01284ApprovedInvestigationalThe complex results in a product whose absorption in man is effected over a longer period of time as compared to corticotropin. Therefore, therapy may be maintained with less frequent administration.
Categories: Sex Hormones and InsulinsSulfadoxine
go.drugbank.com/drugs/DB01299ApprovedInvestigationalWithdrawnA long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.
Categories: Genito Urinary System and Sex Hormones