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Cytochrome c1, heme protein, mitochondrial
go.drugbank.com/bio_entities/BE0003854TargetHumansCytochrome c1 is a catalytic core subunit containing a c-type heme. It transfers electrons from the [2Fe-2S] iron-sulfur cluster of the Rieske protein to cytochrome c … The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase
Polypeptides: Cytochrome c1, heme protein, mitochondrialSynonyms: Cytochrome c-1, Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunitHeterochromatin protein 1-binding protein 3
go.drugbank.com/bio_entities/BE0009101TargetHumansComponent of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity (PubMed:24830416). Mediates chromatin condensation d...
Polypeptides: Heterochromatin protein 1-binding protein 3Synonyms: Protein HP1-BP74Protein S100-A16
go.drugbank.com/bio_entities/BE0008707TargetHumansCalcium-binding protein. Binds one calcium ion per monomer (PubMed:17030513). Can promote differentiation of adipocytes (in vitro) (By similarity).
Polypeptides: Protein S100-A16Synonyms: Protein S100-F, Aging-associated gene 13 proteinProtein S100-A9
go.drugbank.com/bio_entities/BE0008993TargetHumansS100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response (PubMed:12626582, PubMed:15331440, PubMed:16258195, PubMed:19122197 … iNOS-S100A8/A9 transnitrosylase complex is proposed to also direct selective inflammatory stimulus-dependent S-nitrosylation of multiple targets such as ANXA5, EZR, MSN and VIM by recognizing a [IL]-x-C-x-x
Polypeptides: Protein S100-A9Synonyms: S100 calcium-binding protein A9, Migration inhibitory factor-related protein 14Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
go.drugbank.com/bio_entities/BE0000906TargetEnzymeHumansThe protein kinase activity regulates lipogenesis: upon phosphorylation at Ser-90, translocates to the endoplasmic reticulum and catalyzes phosphorylation of INSIG proteins (INSIG1 and INSIG2), thereby … and promotes an atypical serine protein kinase activity using GTP as donor (PubMed:32322062).
Synonyms: Serine-protein kinase PCK1, PEPCK-CConserved protein
go.drugbank.com/bio_entities/BE0003066TargetMycobacterium tuberculosisPolypeptides: Conserved proteinSynonyms: F420-dependent proteinProtein ERGIC-53
go.drugbank.com/bio_entities/BE0002119TargetHumansThe LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins … May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both.
Polypeptides: Protein ERGIC-53Synonyms: ER-Golgi intermediate compartment 53 kDa proteinProtein S100-A8
go.drugbank.com/bio_entities/BE0008955TargetHumansS100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. … iNOS-S100A8/A9 transnitrosylase complex directs selective inflammatory stimulus-dependent S-nitrosylation of GAPDH and probably multiple targets such as ANXA5, EZR, MSN and VIM by recognizing a [IL]-x-C-x-x
Polypeptides: Protein S100-A8Synonyms: Urinary stone protein band A, S100 calcium-binding protein A8Protein S100-P
go.drugbank.com/bio_entities/BE0001191TargetHumansIn a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial
Polypeptides: Protein S100-PSynonyms: Protein S100-E, S100 calcium-binding protein PProtein S100-A2
go.drugbank.com/bio_entities/BE0003602TargetHumansMay function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth
Polypeptides: Protein S100-A2Synonyms: Protein S-100L, S100 calcium-binding protein A2