Search

Displaying results 1801 - 1810 of 10000 in total
  1. Pathway

    Rizatriptan Mechanism of Action Action Pathway

    smpdb.ca/view/SMP0126998
    Drug action

    Rizatriptan is a triptan used to treat migraines with or without aura. Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Rizatriptan is not indicated for the prophylactic therapy of migraine n...

    Drugs: ATP · Rizatriptan · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  2. Pathway

    Dihydroergotamine Mechanism of Action Action Pathway

    smpdb.ca/view/SMP0127001
    Drug action

    Firstly, DHE's s agonist action on 5-hydroxytryptamine (5HT) 1b receptors in the smooth muscle of the cranial vasculature may provide relief via vasoconstriction of the blood vessels which typically become

    Drugs: ATP · Dihydroergotamine · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  3. Drug

    Glutathione

    go.drugbank.com/drugs/DB00143
    ApprovedInvestigationalNutraceutical

    It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides. … A tripeptide with many roles in cells.

    Synonyms: Glutathione-SH, 5-L-Glutamyl-L-cysteinylglycineMixtures: RE-GLUTATHIONE + VITAMIN C Capsule, VitaHealth L-Glutathione Plus
  4. Drug

    Urofollitropin

    go.drugbank.com/drugs/DB00094
    ApprovedVet approvedWithdrawn

    The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24. … It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids.

    Mixtures: Fertinorm Hp 75 - Pws Diluent Im Sc, Fertinorm Hp 150 - Pws Diluent Im ScCategories: Sex Hormones and Modulators of the Genital System
  5. Drug

    Selegiline

    go.drugbank.com/drugs/DB01037
    ApprovedInvestigationalVet approved

    (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability.

    Synonyms: L-DeprenalinCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein inhibitors
  6. Drug

    Xenon-133

    go.drugbank.com/drugs/DB09315
    Approved

    Xenon-133 is an inhaled radionuclide used for lung imaging, imaging blood flow in the brain, and to assess pulmonary function.

    Synonyms: Xenon (133 xe), Xenon Xe 133Products: Xenon, Xe-133
  7. Drug

    Sparsentan

    go.drugbank.com/drugs/DB12548
    ApprovedInvestigational

    Sparsentan is a dual antagonist of the endothelin type A receptor (ET<sub>A</sub>R) and the angiotensin II (Ang II) type 1 receptor (AT<sub>1</sub>R) with a similar affinity for both (9.3 nM for ET<sub … [L45300] On April 24, 2024, sparsentan was granted conditional marketing authorization by the European Commission for the treatment of adults with primary IgAN.[L51559]

    Categories: Agents Acting on the Renin-Angiotensin System, Angiotensin 2 Receptor Blocker
  8. Drug

    Neon

    go.drugbank.com/drugs/DB11589
    Approved

    It is the fifth most abundant chemical element in the universe by mass but a rare element on Earth. … Neon may be used in the clinical setting as a diagnostic tracer gas in a gas analyzer for a lung diffusion test.

    Mixtures: Co-NE-O2-N2 Mixture, Lung Diffusion Test Mix No Ne CoSynonyms: Ne
  9. Pathway

    Frovatriptan Mechanism of Action Action Pathway

    smpdb.ca/view/SMP0126999
    Drug action

    Frovatriptan is a second generation triptan 5-HT receptor agonist that binds with high affinity for 5-HT1B and 5-HT1D receptors. It is structurally distinct from, but pharmacologically related to other selective 5-HT1B/1D receptor agonis...

    Drugs: ATP · Frovatriptan · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  10. Pathway

    Ergotamine Mechanism of Action Action Pathway

    smpdb.ca/view/SMP0127000
    Drug action

    Ergotamine is an alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches. Ergotamine acts on migraine by one of two proposed mechanisms: 1) activation of 5-HT1D receptors lo...

    Drugs: ATP · Ergotamine · Calcium · Magnesium cation · Cyclic adenosine monophosphate · Pyrophosphoric acid
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1