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L-Acetylleucine
go.drugbank.com/drugs/DB16956ApprovedInvestigational[A264439] In September 2024, the FDA approved levacetylleucine for the treatment of select patients with NPC.[L51444] … DL-) form has been available in France since 1957 for the treatment of vertigo.
Apalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalHigher prostate-specific antigen (PSA) and shorter PSA doubling time (PSA DT) are associated with a higher risk for metastases and death [A31846]. … Apalutamide is the first FDA-approved treatment for non-metastatic, castration-resistant prostate cancer [L1295].
Tegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawnNovartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).
Pancrelipase amylase
go.drugbank.com/drugs/DB11065ApprovedInvestigational[L2512] The pancrelipase mixture, including pancrelipase amylase, was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.[L2510]
Synonyms: 1,4-alpha-D-Glucan glucanohydrolaseMixtures: KREON MIKRO 5000 IU MINIMIKROSFER,Succinic acid
go.drugbank.com/drugs/DB00139ApprovedInvestigationalNutraceuticalA water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters.
Eptinezumab
go.drugbank.com/drugs/DB14040ApprovedInvestigational[F94,A33105,A33106,A33108] It was approved by the FDA in February 2020 for the preventive treatment of migraine headaches in adults.[L12318]
Flavin mononucleotide
go.drugbank.com/drugs/DB03247ApprovedInvestigational[A274616,L54226] FMN is composed of an isoalloxazine ring - which serves as the active redox center - attached to a ribityl phosphate chain. … [L54226] In addition to its systemic use as a means of riboflavin supplementation, a topical ophthalmic preparation of FMN was approved by the FDA in October 2025 for use as a photoenhancer in epithelium-on
Mixtures: Alsimine W Vitamins A D, Tonicol Et A-D-C Ampoules/comprimesOmadacycline
go.drugbank.com/drugs/DB12455ApprovedInvestigationalOmadacycline has been used in trials studying the treatment of Bacterial Pneumonia, Bacterial Infections, Community-Acquired Infections, and Skin Structures and Soft Tissue Infections. Omadacycline represents a significant advance over t...
Dupilumab
go.drugbank.com/drugs/DB12159ApprovedInvestigationalIt was first approved by the FDA in 2017. … It is currently used to treat atopic dermatitis, asthma as an add-on maintenance treatment, chronic rhinosinusitis with nasal polyposis, and eosinophilic esophagitis.