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Displaying results 1831 - 1840 of 10000 in total
  1. Drug

    N-Acetylglucosamine

    go.drugbank.com/drugs/DB00141
    ApprovedInvestigationalNutraceutical

    The N-acetyl derivative of glucosamine.

    Synonyms: N-Acetyl-D-glucosamine, aldehydo-N-acetyl-D-glucosamine
  2. Drug

    Palbociclib

    go.drugbank.com/drugs/DB09073
    ApprovedInvestigational

    It is a second generation cyclin-dependent kinase inhibitor[A176798] selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. … Palbociclib is a piperazine pyridopyrimidine[A176792] that acts in the cell cycle machinery.

    Synonyms: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-8h-pyrido(2,3-d)pyrimidin-7-one, 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one
  3. Drug

    Mepolizumab

    go.drugbank.com/drugs/DB06612
    ApprovedInvestigational

    Mepolizumab was first approved by the FDA on November 4, 2015, as an add-on therapy for severe asthma and marketed under the brand name Nucala by GlaxoSmithKline. … This indication was subsequently expanded to cover EGPA on December 12, 2017, and HES on September 25, 2020.[L16518]

    Products: NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML, Nucala 100mg/ml Solution for Injection in pre-filled pen (Autoinjector)
  4. Drug

    Fluticasone

    go.drugbank.com/drugs/DB13867
    ApprovedInvestigationalWithdrawn

    [DB00588] was first approved in 1990[L5962] and [DB08906] was approved in 2007[L5965].

    Mixtures: Fludalt DUO 250/50mcg Inhalation Powder Hard Capsules
  5. Drug

    4-(Isopropylamino)diphenylamine

    go.drugbank.com/drugs/DB14195
    Approved

    4-(Isopropylamino)diphenylamine, also known as IPPD, is a chemical compound commonly used as an antiozonant in rubbers, particularly those used for tires. It is also a known allergen.

    Synonyms: N-Fenyl-N'-isopropyl-p-fenylendiamin, 1,4-Benzenediamine, N-(1-methylethyl)-N'-phenyl-Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Acetohexamide

    go.drugbank.com/drugs/DB00414
    ApprovedWithdrawn

    A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.

    Synonyms: N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea, 1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamideCategories: Drugs Used in Diabetes
  7. Drug

    AS-8112

    go.drugbank.com/drugs/DB09207
    Experimental

    AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. … It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use.

    Categories: Dopamine D2 Receptor Antagonists
  8. Drug

    RUTI® Vaccine

    go.drugbank.com/drugs/DB15853
    Investigational

    Much like the BCG vaccine, the RUTI® vaccine is also being tested as a prophylactic for SARS-CoV2. … Sponsored by Fundació Institut Germans Trias i Pujol, the RUTI® Vaccine is being tested for prevention of COVID-19 infection in a controlled trial with 315 healthcare worker participants (NCT04453488).

  9. Drug

    Hydroxyurea

    go.drugbank.com/drugs/DB01005
    ApprovedInvestigational

    [A262601] Although clinical evidence on the efficacy of hydroxyurea in certain conditions exists, hydroxyurea is used sparingly in clinical settings, largely due to lack of knowledge and adherence, the … [A262596] It was first approved by the FDA in 1998 for the treatment of sickle cell anemia in adults.

    Synonyms: N-Hydroxyurea, N-Carbamoylhydroxylamine
  10. Drug

    Thonzylamine

    go.drugbank.com/drugs/DB11235
    Approved

    Thonzylamine is an antihistamine and anticholinergic drug.

    Mixtures: Poly-Hist DM