Search
Phenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approvedPhenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants. … [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications
Mixtures: Dilantin W Phenobarbital 15mg, Dilantin W Phenobarbital 30mg CapCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexCaffeine
go.drugbank.com/drugs/DB00201ApprovedInvestigational[L9863] According to an article from 2017, more than 15 million babies are born prematurely worldwide. This correlates to about 1 in 10 births. … [A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, which are different than coffee beans.
Mixtures: GERALGINE-K 500 MG/30 MG/10 MG TABLET, 20 ADET, THOMAPVRIN 250 mg/200 mg/50 mg TABLET, 10 ADETCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesAmuvatinib
go.drugbank.com/drugs/DB12742InvestigationalAmuvatinib is an oral, selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and the mutant forms of c-KIT, PDGFR and FLT3. … Amuvatinib also suppresses Rad51 protein, a critical component of double-stranded DNA repair in cancer cells.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-[1]Benzofuro[3,2-D]Pyrimidin-4-Yl-N-(1,3-Benzodioxol-5-Ylmethyl)Piperazine-1-Carbothioamide, 1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro(3,2-d)pyrimidin-4-yl-Benzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalAlthough the indazole analogue benzydamine is a non-steroidal anti-inflammatory drug (NSAID), it has various physicochemical properties and pharmacologic activities that are different from those of traditional … It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system.
Mixtures: KLOROBEN FORT 3 MG/ML+ 2 MG/ML ORAL SPREY, 40 ML, TANTUM VERDE DUO FORTE 45 MG+18 MG/15 ML GARGARACategories: Heterocyclic Compounds, 1-Ring, Non COX-2 selective NSAIDSNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide is a first-line, standard treatment for illness caused by C. parvum or G. lamblia infection in healthy (not immunosuppressed) adults and children and may also be considered in the treatment … It is generally well tolerated.
Categories: Heterocyclic Compounds, 1-RingProducts: NITAZOXANIDA 20 MG / ML POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL, VIBATRIN® 100 MG / 5 MLDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and
Mixtures: Cosopt 20 mg/ml + 5 mg/ml Augentropfen, DUOSOPT FREE 20 MG+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 60 ADETCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesLovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … [A181087, A181406] Lovastatin and other drugs from the statin class of medications including [atorvastatin], [pravastatin], [rosuvastatin], [fluvastatin], and [simvastatin] are considered first-line
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsSynonyms: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate, 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactoneMavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigationalIt received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. … Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM).
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2B6 InducersSynonyms: 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dioneRisedronic acid
go.drugbank.com/drugs/DB00884ApprovedInvestigationalIt functions by preventing resorption of bone[FDA Label][A959]. … Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Mixtures: RISEPLUS D3 35 MG/2800 IU EFERVESAN TABLET, 12 ADET, RISEPLUS D3 35 MG/5600 IU EFERVESAN TABLET, 12 ADETCategories: Heterocyclic Compounds, 1-RingPinometostat
go.drugbank.com/drugs/DB12920InvestigationalPinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
Synonyms: 9H-PURIN-6-AMINE, 9-(5-DEOXY-5-((CIS-3-(2-(6-(1,1-DIMETHYLETHYL)-1H-BENZIMIDAZOL-2-YL)ETHYL)CYCLOBUTYL)(1-METHYLETHYL)AMINO)-.BETA.-D-RIBOFURANOSYL)-Categories: Heterocyclic Compounds, 2-Ring